I was wrong about saturated fat.

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#JohnnyColeDickson #Saturatedfat #Cholesterol

I was wrong about saturated fat. (read on below).

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CITES

📺Videos: mentioned:
- Ancel keys (butter) video:
- Livestreams:
- Sugar's sneaky impact on your blood:

Personal notes:
It's worth noting that lipids don't exclusively represent structure in the body. They are "concrete and bricks", but they are not ONLY concrete and bricks! Lipids are involved in energy production (think the fat on our bodies) and cell signaling (think membranes of our cells, trafficking, development, regulation + more). Although unlikely (and I haven't found anything of this nature), let's say cholesterol levels are increased by a specific lipid signaling pathway as a direct result of dietary saturated fat intake. Consider again, the weight of cholesterol in the overall conversation. We can rest assured that in the event dietary saturated fat causes more cholesterol production by way of our hypothetical signaling pathway that this would mean, for some reason, the body NEEDS that cholesterol. We must remember, cholesterol is not inherently bad- scratch that, we must remember cholesterol is vital to our existence. And if cholesterol is increased due to this proposed mechanism, we can't assume saturated fat is inherently bad either. Not to mention: cholesterol is a signaling lipid in and of itself.

Okay, what about lipid signalling on the immune system or oxidation production? Everything in the body represents a signal, every action the body takes warrants a pathway. When it comes to lipid signaling, we're regarding a vast and complex array of processes that affect many things, so let's hone it a bit. It's a great thing to know that lipids play crucial roles in communication. Saturated fat and unsaturated fat as we could imagine, don't communicate the same thing in every instance. This system/thought trail of lipid signaling on immunity, (for example, look into PUFA and SFA and macrophage signaling), would propose, I'd argue, the biggest merit for lipid signaling to be involved in the conversation of atherosclerosis (if we're talking specifically lipid signaling). But once we go there, we start to drift from the initial point of any of this: analyzing the most influential scientific message in American food history: the diet heart theory.

Regarding the context, the most relevant mechanism of cholesterol levels changing due to saturated or unsaturated fat intake has much more to do with what's proposed in this video than they do energy production (virtually irrelevant) or lipid signaling (bike shedding).

"Despite their ubiquitous presence, it is rare that a signaling
lipid is diagnosed as a causative agent in disease." [C]

Okay, but Johnny, aren't you being a bit too specific when you say things like "there is no mechanism for the saturation of a fat to influence cholesterol directly?" What about the interventional studies that show saturated fat increases cholesterol levels? For starters, consider the study's details, are they measuring by comparison[D] (SFA replaced by carb, protein, or PUFA)? Are they measuring quantity of LDL/cholesterol at all? or are they measuring quality?[E]. Were participants given ungodly amounts of SFA that wouldn't translate into "real world" application?[F (although, I do think this experiment is pretty cool!)]. Did the participants already have a preexisting condition?[G]. Were humans measured? We also must be careful to differentiate between LDL and cholesterol. But let's say we're talking about LDL (I'd argue most research is), remember LDL is benign until modified. There are types of LDL particles that are more susceptible to this "modification". So, the question to ask is: does saturated fat increase the chance of LDL becoming modified? Here's a narrative review of where the conversation is currently:[H].

Personal notes cont.

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🟡🔋LMNT - get a free sample pack with any purchase!

NoLabCoatRequired
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I can’t adequately express how much I love your presentation style. The cadence of your speech, the graphics, the humor and especially the substance … it’s all terrific. Thank you!

jedwards
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There is a thing called French paradox which is about how the French generally have low heart disease rates despite consuming a lot of saturated fat. That alone should be proof enough that saturated fat isn't as bad as commonly believed

BlindBosnian
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I had to get a full blood panel for work. When the doctor sat down with me he was shocked at my cardiovascular health markers, asking if I was vegan and asking what exactly I did to get numbers as low as I had. My LDL was 66mg/dl and my triglycerides were 40 mg/dl. I told him I at 12 whole eggs every day for breakfast and he immediately told me to stop and that I was lucky my numbers were so good.
Dietary cholesterol isn't the problem.

tgs
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Those of us who knew this 30 years ago and more - are quietly enjoying watching everyone discover the joys of butter!

roxannlegg
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Soft and vulnerable, like my generation. Bro you are amazing.

donovanloreman
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Good to see young folks questioning the same things old folks have been suspicious of for decades.

keiththorp
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I completely changed my diet six months ago based on nationally recommended guidelines, but it only made my health worse. It wasn’t until I read 'The 23 Former Doctor Truths' that I realized doing the opposite of what the government advises can actually make a difference. No wonder the doctor who wrote it left their career—speaking the truth often challenges the system!

emiliasokolova
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I don’t buy low-fat products and margarine is not allowed in my home. I personally believe that sugar and high fructose corn syrup are what’s hurting us the most.

HG-gjlh
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Thank you for being better than the scientists and
1) actually admitting if/when you're wrong
2) actually putting out the information as to why you may be right or wrong
3) actually admitting that you/scientists don't yet know many aspects of how things work
4) trying to clarify that absolutes are not always absolute.
Your honesty is appreciated.

Edit: My apologies for lumping all scientists together. More directly, I apologize to scientists who are doing their best for honest research. While I stand by my words, I also know that they do not apply to everyone, as not everybody is the same. I 100% deserve to be roasted on behalf of those who do not fall in the categories mentioned above.

KD-fvmp
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You are one of the best content presenters on the internet. Keep up the Great work!

BruceHurley
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My dad had a quad bypass in his early 40s, in the early 80s. We were told everything had to be low fat, no cholesterol. We were told if it's solid at room temperature, it's solid in the body! That it went directly to the arteries to block them! But broccoli didn't? The recommended diet included a lot of chemically created foods and sugar. It's no wonder we all got fatter and unhealthy!

TracyKMainwaring
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I'm 55 years old. My last three doctors have been desperate to have me take statins, as my cholesterol is around 300. Been that way for 10+ years. I'll continue eating my steaks, eggs, avocados, and bacon.

KaiPonte
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Perfectly timed ad break. I got to drop a deuce and come right back without pausing.

TheRealxKaydo
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Love this man/channel. Right amount of info/editing/humor... So underrated

shootnblankz
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I have HS of the scalp, which is a debilitating disease due to the extreme pain. I've tried everything, spent tens of thousands of dollars on doctors, medications, remedies, and diets. I recently figured out that seed oils were causing this condition. After cutting seed oils out of my diet, I've been in remission ever since. No flare-ups, and not a single doctor appointment for this condition for a solid year. It took me 20 years to figure this out, and the remedy was so simple all along, but it's not at all easy to avoid seed oils. Grocery shopping is hard, and eating out at restaurants is almost impossible. Even the fancy expensive restaurants out here use seed oils, which is really disappointing.

Cyber_Homestead
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I can tell you first hand that higher saturated fat intake combined with lower carb intake, did in fact increase my total cholesterol and LDL. Not just a little but almost tripled my numbers. My doctor freaked out

earthmamma
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I love your work! Such great production quality.

ruppertb
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I eat beef, bacon, butter, eggs and salt. No carbs. My autoimmune conditions have gone into remission and I feel like a real human being again.

barbarahampton
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Bro the algorithm screwed you; i havent seen you since the fasting video, eight months ago.

ORMONDROPON