2 Things to Supercharge Collagen Production by 50%!

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0:00 - Introduction
1:02 - Study Breakdown
1:44 - Collagen Production
3:15 - Inconsistencies in the Data
3:35 - Collagen Breakdown
4:28 - Addressing the Inconsistencies
6:50 - Take-Aways

References
[Study 362] Nulty CD, Tang JCY, Dutton J, et al. Hydrolyzed collagen supplementation prior to resistance exercise augments collagen synthesis in a dose-response manner in resistance-trained, middle-aged men. Am J Physiol Endocrinol Metab. 2024;327(5):E668-E677. doi:10.1152/ajpendo.00252.2024

Funding/Conflicts: Unknown Funding / No Potential Conflicts of Interest

[Study 363] Aussieker T, Hilkens L, Holwerda AM, et al. Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates. Med Sci Sports Exerc. 2023;55(10):1792-1802. doi:10.1249/MSS.0000000000003214

Funding/Conflicts: Industry Funding [Gelita and LB Leiner] / No other Conflicts of Interest

[Study 366] Martínez-Puig D, Costa-Larrión E, Rubio-Rodríguez N, Gálvez-Martín P. Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge. Nutrients. 2023;15(6):1332. Published 2023 Mar 8. doi:10.3390/nu15061332

Funding/Conflicts: None / Potential Conflicts of Interest [Researchers are employees of Industry, Bioiberica]

[Study 367] Khatri M, Naughton RJ, Clifford T, Harper LD, Corr L. The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino Acids. 2021;53(10):1493-1506. doi:10.1007/s00726-021-03072-x

Funding/Conflicts: Industry [Rousselot BVBA] / No other Conflicts of Interest

********CRITIQUES, RULES, AND NOTES********

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#collagen

[Physionic]

2 NOTES
Note 1: Some of you might be aware another study released indicating collagen supplementation did not change connective tissue synthesis (which was covered by Dr. Layne Norton recently). Several things to point out here: one, there is no doubt significant room for re-interpretation of some of the collagen research (it is not a 'sure thing' yet); two, that study (PMID: 39086044) was in younger individuals, so it might indicate collagen is only effective after a certain age (unknown, but suggestive).

Note 2: I mention that collagen supplementation increased collagen synthesis in the body with both collagen conditions, but I made the mistake of not showing the AUC data, so the only data shown indicates a high dose is effective, but not the lower dose. The statement in the video is correct (both doses worked), but I should have shown the AUC data other than just the line data (as shown at 2:51). My apologies.

[Itisrealtalk]

I have seen NOBODY....not even a single researcher or scientist or any learned person like you talk about boosting "Elastin" synthesis naturally. Everyone talks about collagen boosting and related things but there's absolutely no discussion about elastin boosting in humans.

We do lose elastin as well with increasing chronological age and with less of it, our skin sags. I'd love if you could be THAT FIRST PERSON to talk about "naturally boosting elastin production".

Thank You!

[tijmenmolder]

Since collagen is mostly glycine, is there any research on the effect of glycine supplementation on collagen production?

[ConniePretula]

One of my clients injured his ACL and MCL running, he was 66 at the time. I put him on Hydrolyzed Joint Collagen, Hyaluronic Acid and Boswellia. He stopped running to let everything heal. His doctor told him he would never run again 🤔 He walked regularly to stay fit. After a year, he decided to try running again and did not have any pain in his knee. He is running 5 days a week and some weeks a total of 40 km. His doctor was amazed at his recovery. This was enough for me to confirm the benefits of a quality collagen product. I should add, he did not have surgery to repair his ACL or MCL.

[gasparsigma]

I wish they had one more group for consuming high quality protein (like Whey) to compare against

[scottymackay]

I've been on and off collagen several times testing it. Have seen zero benefit in skin improvement (although my skin is pretty good) but did notice the knees feeling better each time I went back on. It was enough to convince me to keep taking it.

[jaymehatfield]

Yet another topic we all need to learn and presented in your concise, methodical manner thanks

[superpauleesworld]

OMG love your decor/pics for these vids! And that pink floor light shining up! lol! You are so funny, brilliant yes, funny too yes! And what IS that small pic? It looks like a dark scary mask on an alien or something! 🤣 But you get away with it all because you're so freekin' brilliant!! Love your vids - all of them bro!

[pianogirl]

I gobble up your interesting findings....very much appreciated!

[zaya]

Taking 30g of collagen a day has helped my joint pain so much more than when I was taking 20-22ish grams. I felt the benefits of upping the dose almost instantly.

[dcjohnson]

I’m male(octogenarian). I notice significant skin improvement taking collagen with Hyaluronic Acid.

[Ruktiet]

Would gelatin consumption be equally good as collagen consumption? Thanks for the video

[classicpinball]

Doesn't vitamin C help as well? from food or supplementation

[randomstuff]

gem after gem after gem…..you bloody jeweller 😂😂

[jenxsj]

Hi Dr Verhoeven. I do all that already. I am one of the most collagenased women I know.

[RonaldWhite-dr]

Normotim is definitely worth trying! I feel calmer and more confident thanks to it. Has anyone else already tried it?

[esther.f.g]

I can't mesure the impact on cartilage and connective tissue but I experience a very positive impact on my skin, hair and nails after using collagen, and I am not the only one. I think that there is a positive impact but it depends on what is the purpose of the use of collagen

[grunchidetrap]

Crazy coincidence, just bought a high quality collagen supplement for the first time today

[livephysiology]

"It’s an important first step" seemed like a nice way of Physionic to describe the research at this stage.

[zachcain]

Did they match for protein intake between the 3 groups?