Non-Hodgkin's Lymphoma

You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:

** Correction at 1:09:30 - 1:10:51: **

The Ann Arbor Staging looks at the position of involved Lymph nodes on the SUPERIOR and INFERIOR positions regarding the diaphragm, not the left or right hemidiaphragm. In other words, Stage II would have 2+ LN’s above OR below the diaphragm, but can only be on one of those sides. Stage III would have 2+ LN’s both above AND below the diaphragm.

Of note, the Ann Arbor staging has fallen out of favor for NHL and was recently replaced with the Lugano classification.

Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Non-Hodgkin's Lymphoma. Non-Hodgkin Lymphoma (also known as NHL, or sometimes just lymphoma) is a cancer that starts in white blood cells called lymphocytes, which are part of the body’s immune system.

NHL usually starts in lymph nodes or other lymph tissue, but it can sometimes affect the skin. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:07 Non-Hodgkin’s Lymphoma Introduction
0:50 Lymphocyte Pathway
16:22 Causes of Increased Neoplastic Lymphocytes (B-Cells)
32:36 Effects of Increased Neoplastic Lymphocytes (B-Cells + T-Cells)
53:22 Diagnostic Approach to Non-Hodgkin’s Lymphoma
1:06:14 Staging of Non-Hodgkin’s Lymphoma
1:13:05 Treatment
1:19:31 Comment, Like, SUBSCRIBE!

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[Delatta]

Great presentation. I was diagnosed with MZS Lymphoma, Stage IV (low grade) in 2005, only 5 years after retiring from the Army as a Aviator. I was 43. The one thing I think is very important for diagnosis is how my symptoms presented themselves. Dry cotton mouth, severe itching (mainly where my clothes touched my skin tightly), night sweats, periodic fevers with no infection, and very severe fatigue. I never contributed any one of them to be part of the collective issue. I like to think I’m educated and informed, but there was no way I could have connected them all to NHL. Even the doctors were baffled. I was admitted to the hospital, and for a week I was the Guinea pig for about a dozen residents. There’s nothing more concerning when it comes to my health then watching doctors scratch their heads and not have answers. It took a bone biopsy to find the truth. After my enlarged spleen was removed, I went through CHOP (I wouldn’t wish it on anyone), and maintenance treatment for 4 years. I’m still in the fight, and the key for patients is to stay aggressive and informed in your treatment. Including the PET scans and labs as often as possible. What you presented here really helped me understand the process of how it progressed. Thanks

[vetnet]

Best medical and physiology videos anywhere on the internet! Thank you for your dedication!

[atiqrahman]

I have non-hodgkin mantle cell lymphoma. Going through RBAC chemo after 7 cycle of Retoximab and acalabrutinib. Not sure why RCHOP shows everywhere to tackle the cancer. Presentation was mind blowing, the best so far in YT. Thank you!!

[carriesmotherman]

I live vicariously through you. Before I was struck by lightning, I tutored physics, chemistry and calculus. I discovered you exploring Hodgkins lymphoma as I have many symptoms and am trying to get referred to an oncologist.
Your videos are amazing! I miss teaching so very much.

[Borkstar]

Seriously the best comprehensive, detailed and yet effective explanation I’ve seen on the internet

[georgebashour]

Thank you .. This video is on time for my last semester in medical school ...having Hematology in a month! ... This surely made everything way easier

[eternitystudent]

Excellent. As an oncologist I can say that this lecture is so true and important for common understanding

[elinaparkkonen]

Once again a huge THANK YOU Ninja Team💕 for all your hard work. Team work makes the dream work. All my love to you all. Happy midsummer from Finland 🇫🇮👋!

[mopthefloor]

I’m so glad you are making haematology videos because I have an exam in a week and these are the only thing that makes sense to me. Thank you !!!!

[manojkahar]

One of the best lecture ever attended on Non Hodgkin Lymphoma ever attended or learnt in my life...too too good...no words to describe the marvellous way in which the concepts are given by the presenter...hats off to you sir

[alextukundane]

Your dedication to sharing knowledge across the world is unbelievable, Thanks so much

[anvisaini]

This should be paid. THANK YOU SO MUCH

[elcancerynosotros.]

Thanks a lot! Excellent presentation! Zack, you have a natural uncanny set of skills to teach!!!

[yeikalarrinaga]

Amazing lecture! Thank you very much for your dedication

[venusdarkside]

I was diagnosed with hodgkins lymphoma a year ago my chemo is complete and excited to study the hodgkin and non hodgkin as a med student

[jeanpaulrukabyarwema]

I have been looking for this after watching Hodgkin lymphoma

[shahiramohammadi]

Thanks for this content I don't realize this much in class❤

[samruddhimahadik]

Absolutely the best explanation I have ever received on this topic, even paid platforms fail to give such detailed and understandable explanation ❤

[okorobepascalmathew]

Genius . saved my time instead of cluelessly staring at the text books

[vramj]

I had NO symptoms other than a almond sized lump in my neck. Thought it was an infection. 1 month turned into several lumps that started pressing on my windpipe. I was lucky I had a DR that LISTENED to me and took me seriously.