Nicotine Receptors in the Brain: Implications for Addiction and Depression

Each month The Brain & Behavior Research Foundation hosts a Meet the Scientist Webinar featuring a researcher discussing the latest findings related to mental illness. In October, 2018, the Foundation featured Dr. Marina R. Picciotto of Yale University School of Medicine.

Description: Nicotine is the primary addictive component of tobacco. We now know a great deal about the targets for nicotine in the brain and the circuits involved in its behavioral effects. There is also a longstanding association between tobacco smoking, anxiety and depressive disorders. In this presentation, I will discuss studies in mice and humans that have identified the targets and brain areas that are important for the addictive effects of nicotine and how this relates to brain circuits that are impaired in individuals with anxiety and depression.

[HairGlitter]

I found a case where a nicotine patch was used to stop a 5 year old from having 50 seizures a night. She was resistant to medications. We need more research

[LindaLundinColoringBooks]

So the biggest lie is that governments can force whole cities to stay home but they can't stop selling ciggarettes. Can someone explain this to me?

[lunaticatiga]

So ciggartes can cause or contribute to depression? 😳

[sarahpamula]

Science/Physics: A City in Southern France/ pleasant. Nice/nice🎉

[HmmmVeryCurious]

Oh My word you guys!! Thank you so much for creating this. This is incredible work here. I love the level of detail covered in this video by Dr. Picciotto!! I am absolutely enthralled, and resolutely subscribed to your channel, and wait with bated breath for your release of more. Thank you thank you thank you. this is so much more illuminating and digestible than a lit review!!

[sapper]

Why is everything “might” or “we think” when can we get ourselves actually data and not “hypothesis”.

[kevinfrench]

After listening to the long rambling intro I need a cigarette

[nnaxtt]

So what I'm understanding is that because these smokers are actively opening and blocking their receptors sometimes they block the amount of ACh in the brain which can cause symptoms if too much ACh is in the brain?

[oaktree]

So I have suicidal depression and an also hopelessly addicted to nicotine. When i don't have nicotine I go through withdraws to the extreme. If i get antidepressants that would be a good thing?

[prithvirajrana]

It does not say that in how many days the nicotine receptor will be completely removed from the brain.

[c_farther]

I don't want to hear someone on the phone; I can't believe this video is so awful. Thumbs down.

[Meanwoman]

Are there any studies in the works for LSD and quit smoking? LSD and depression?