VDJ recombination overview | Generation of antibody diversity | Antibody diversity mechanism | VDJ

This video gives a birds eye view on VDJ recombination and generation of antibody diversity.

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For Physics part of bio exams - Physics for IIT JAM biotechnology

#VDJ #VDJrecombination #vdjrecombinationoverview #antibodydiversity #generationofantibodydiversity #antibodydiversitymechanism #Bcells
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[Science_afterhours]

I'd like to thank you for this - I'm doing a MSc in Immunology and the textbook explains this process poorly in my opinion. So have saved me hours of confusion.

[MistyKoiFish]

I'm currently working on a culmination project for a high school program and let me tell you... thank you! This cleared up a lot of confusion I had while researching the topic of the B cells in the immune system. I finally now understand why there are so many different combinations and why the immune system recognizes so many different pathogens.

[kamnagupta]

This helped so much! Current med student in the US-thanks!

[tioadekola-ojo]

Very informative video. Was able to better understand antibody diversity for my upcoming exam tomorrow, thank you!

[Lets-give-a-try]

Complete information in just 11 minutes❤❤❤

[aminajoliedaou]

🥹🥹thank you for your explication you saved my life ❤️❤️it’s so much clear right now in my head

[milocrawford]

Thank you man, for real, I was having a breakdown hear because I couldn't understand shit about VDJ lol

[tanmoysen]

Dada, if you do videos on specific section and make playlist of those videos just like you had done on CELL SIGNALLING that will be very helpful for us inspite of overview videos ....specially for people like me ( did not get much help from teachers)...
I hope you will look into this request ....and keep doing amazing videos like this ...

[carlettagoodrich-mann]

Madame Curio ‘s protocols for genomes. Curing the immune system. Matters.

[dogbeygodwin]

well explained but please take note that B cells mature in the bone marrow

[rashmiranjansahoo]

I have read that human contains 44 variable gene segments on heavy chain and u say 57.Can u justify it.

[matteobarca]

Thank you, I finally understood it. Just a question, when you say there is a Flexibility that generate a lot of variability, you mean there are several points in which RAG1and2 could operate?
Thanks a lot and a big hug from Italy

[harshithamohan]

Thank you....
Plz make a video on Ramachandran plot...

[jayanthijayaraman]

Excellent presentation will be helpful if heavy chain gene rearrangement is presented in Vol. II

[noah-battlegroundsmobileindia]

At 10:32 total Vh gene segment mentioned is 51. Isnt that 40? 40x27x6=6480.
Or what is the source of this information?

VDJ mechanism is poorly explained here..it does cover the background..but according to the title it should be focusing more on VDJ recombination itself

[charliebrett]

Hey! where exactly does this take process take place with respect to chromosomes. I get it takes place in developing B cells. Also for context we get 23 chromosomes from each parent and VDJ happens at specific chromosomal loci AND chromosomal DNA is double stranded. So my question is does this process take place on one chromosome pair or just on a singular chromosome? Also must these chromosomes be replicated prior to VDJ recombination? Thanks so much

[bivasnag]

greatly explained but so u have any method to remember this terminology

[michaelh]

still havent explained how you can billions of different alleles.

[samarthkumar]

In which segment of Variable region CDR's are present?