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Costas Maranas Discusses His Latest Work in Metabolic Engineering
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AIChE’s Steve Smith discusses Costas’s latest book, Optimization Methods in Metabolic Networks, which was co-authored by Ali R. Zomorrodi. The volume explores tools and solutions for mathematical optimization concepts and representations for the curation, analysis, and redesign of metabolic networks. It aims to apply the language and tools of mathematical programming to describe and solve common tasks such as calculation of product yield, gene essentiality prediction, identification of network gaps in the model, resolution of discrepancies with experimental data, and identification of network modifications that increase product yield.