Intro to Reaction Mechanisms: Crash Course Organic Chemistry #13

When we venture to new places, we need navigational tools to guide us. In organic chemistry, those are reaction mechanisms! In this episode of Crash Course Organic Chemistry, we’ll learn all about how to write reaction mechanisms. Having this super useful skill means we don’t have to worry about memorizing every reaction that has ever existed.

Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.

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[jamaiya]

this is where o-chem all went downhill for me 🥴

[drakesmith]

To anyone who hasn’t studied Organic Chemistry a bit, forewarning it’ll be bad at first, but it will get better. Mostly I mean reaction mechanisms here but in general. You’ll feel more satisfied and more motivated the more you go on.

[iveight]

To the person that’s reading this:

You’re very intelligent and adorable human!
Stay healthy during quarantine

My Dream is to have 70k. I been struggling to get there💚

[MoMn.]

Production values are exceptional. Huge respect to your awesome animators

[mathfincoding]

I lost track of what's happening 10 episodes ago. This isn't even my major. I don't know why I'm still watching 😂

[firefx]

I just can't take my eyes off of the background colors matching in yellow.. 😂

[SciFactsYT]

Random fact:

Blue whale tongues can weigh as much as an elephant.

[henryelicker]

I wonder what the mechanism is for "Turn the O2 into the O3, dawg".

[marinabarros]

omg you're such a good teacher. I've already had all my org chem classes and I still don't understand a lot of the basic stuff. My teachers actually didn't bother to teach us this :/

[getrektfn]

“Who else is reading comments and not watching in full screen?😂”

*(Hey CrashCourse thanks for commenting on my new video)❤️*

[aceroro]

why is water still floating? i’ve never been able to grasp why it is still there

[zulanova]

FINALLY, I GET IT
thank you ever so much that was a wonderful and clear explanation, and the visuals really helped

[ishikasingh]

You guys, seriously, LIVE SAVIOURS. My organic chemistry course is starting next week. Can you imagine my sheer relief at seeing this course on ur channel? Thanks!

[jacobkelly]

Why doesn't the HSO4 negative charge attack the carbocation more readily than the water? Steric hinderance?

[Dmplivemail]

It would be so great if after this classes we had some exercises...

[benjaminstandefer]

Thank you for the video. Have you ever considered creating a course oriented more towards mathematics? I am an avid fan of your videos, but often have to turn to other resources for mathematical help.

[ramjayadeepb]

Corona:"I spread fast"
Me: "not faster than crash course views"😎

[benscrafield]

A few misleading things in this video. First of all a lot of the structures are not great: molecular geometries were wrong for sulfuric acid and H3O+, and there’s the tendency to show square-planar-type structures for organic molecules - obviously people do this for the purpose of teaching, but then when you want to show a mechanism, e.g. an elimination, you need to introduce another method of representation for it to make sense. Speaking of which, the reversible hydration/dehydration would surely give the E alkene as the major alkene component, very quickly. As presented in the video, it makes it look like you would have a mixture of the Z alkene and the alcohol, which effectively would not be true. Also the reference to pKa was quite odd: why state that the protonated alcohol has a low pKa if it’s not going to be compared to H3O+ in the forward direction?

[jennadodge]

I got most of it but what happened to the HSO4? Why was it not added to the reaction

[uerkbyj]

Just in time for my quiz later. Thank you.