Bone elongation - processes at the epiphyseal plate

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• Interstitial lengthening occurs in only certain bones, primarily those of the appendages.
• Such lengthening takes place at the epiphyseal plate, a layer of hyaline cartilage in the metaphysis of a growing bone.

1. Zone of resting cartilage.

• Consisting of a hyaline cartilage pad made of inactive chondrocytes, this zone anchors the plate to the epiphysis.

2. Zone of proliferating cartilage.

• The mitotic proliferation of chondrocytes in this zone pushes the resting cartilage outward, helping to lengthen the diaphysis.

3. Zone of hypertrophic.

• In this zone, chondrocytes are stimulated to mature and enlarge, helping to lengthen the diaphysis.

4. Zone of calcified cartilage.

• This thin zone of dying and dead cartilage cells cements the epiphyseal plate to the diaphysis and borders the creation of new bony matrix.

• Osteoclasts remove the calcified cartilage and make way for osteoblasts to build new spongy bone trabeculae.

• proliferation of chondrocytes increases cell number.
• The increased numbers of chondrocytes enlarge, moving the epiphysis away from the diaphysis. This increases the length of the bone.
• The larger amount of dying cartilage tissue is replaced with bone matrix thereby solidifying the resulting elongation.

[nobhk]

Quick and Clear explanation thank you!

[sameerhinduja]

That's great informative video so how many years before we can finally manipulate adult growth plates?

[tahsenhossain]

Can i see my growth plates from normal knee x-ray?

[georgeglenbuenaflor]

thanks for the info! it helps ne a lot

[PadsterX]

great video! one question: by good nutrition, exercise and sleep bones grow quicker, but does it also mean the ephiphyseal plate closes faster? are people suffering from malnutrition shorter because their bones didn't grow enough to close the ephiphyseal plate?

[Dietitian.Manahil.]

What this less number of subscriptions?😑

[theinvertedprotagonist]

In your opinion, can sleep deprivation and depression affect this process? Thus a kid won't achieve their maximum potential adult height.

[prajwalravi]

Hey, I'm 20 n 5'7(dad-5'7--mom-5'3)
Will I grow or not??
Thanks