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Pandemic science, Wear a mask to protect yourself
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All referenced hyperlinked below for personal perusal and verification. CDC
Masks reduce the spray of droplets when worn over the nose and mouth
Prevent people who have COVID-19 from spreading virus to others
Respiratory virus shedding in exhaled breath and efficacy of face masks (Nature Medicine)
Aerosol transmission is a potential mode of transmission for coronaviruses as well as influenza viruses and rhinoviruses
Universal use of face masks for success against COVID-19: evidence and implications for prevention policies (European Respiratory Journal)
Cloth masks are a simple, economic and sustainable alternative to surgical masks as a means of source control of SARS-CoV-2 in the general community
Mask wearers are dramatically less likely to get a severe case of Covid-19
Professor Monica Gandhi, San Francisco General Hospital.
No mask is perfect
Wearing one might not prevent you from getting infected
But it might be the difference between a case of Covid-19 that sends you to the hospital and a case so mild you don’t even realize you’re infected.
Masks Do More Than Protect Others During COVID-19: Reducing the Inoculum of SARS-CoV-2 to Protect the Wearer (Journal of General Internal Medicine)
Universal masking reduces the “inoculum”
Leading to more mild and asymptomatic infection manifestations
Masks, depending on type, filter out the majority of viral particles, but not all
Viral inoculum and severity of disease (LD50)
Rising rates of asymptomatic infection with population-level masking
Increased with mask wearing, decreased where few masks are worn
So, more asymptomatic infections
Greater community-level immunity and slower spread
Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach (Annals of Internal Medicine)
The point is not that some particles can penetrate but that some particles are stopped
Every virus-laden particle retained in a mask is not available to hang in the air as an aerosol or fall to a surface to be later picked up by touch.
Cloth can block droplets and aerosols, and layers add efficiency.
Immunity and immunopathology to viruses: what decides the outcome? (Nature, Reviews Immunology)
The outcome of host–viral interactions depend on
Dose and route of infection
Viral virulence properties
Several host factors that mainly involve innate and adaptive immunity
If the exposure dose is very high, the immune response can become overwhelmed.
If the initial dose of the virus is small, the immune system is able to contain the virus with less drastic measures.
If this happens, fewer symptoms, if any
A simple method of estimating fifty per cent end points, (American Journal of Hygiene, 1938)
Viral dose being related to disease severity
Validation of the Wild-type Influenza A Human Challenge Model H1N1pdMIST: An A(H1N1)pdm09 Dose-Finding Investigational New Drug Study (Clinical Infectious Diseases)
Clinical symptoms of influenza occurred at all doses (Table 1), but were most prevalent at 106 and 107 TCID (tissue culture infectious dose)
Higher viral doses, the more sick people became
Simple Respiratory Protection—Evaluation of the Filtration Performance of Cloth Masks and Common Fabric Materials Against 20–1000 nm Size Particles, (The Annals of Occupational Hygiene)
Masks increase the rate of asymptomatic cases, (Annals of Internal Medicine)
COVID-19: in the footsteps of Ernest Shackleton, (MBJ, Thorax)
Cases at seafood plant cause spike in Oregon COVID numbers (Pacific Seafoods)
Releases Covid-19 Test Results at Northwest Arkansas Facilities (Tyson)
Masks reduce the spray of droplets when worn over the nose and mouth
Prevent people who have COVID-19 from spreading virus to others
Respiratory virus shedding in exhaled breath and efficacy of face masks (Nature Medicine)
Aerosol transmission is a potential mode of transmission for coronaviruses as well as influenza viruses and rhinoviruses
Universal use of face masks for success against COVID-19: evidence and implications for prevention policies (European Respiratory Journal)
Cloth masks are a simple, economic and sustainable alternative to surgical masks as a means of source control of SARS-CoV-2 in the general community
Mask wearers are dramatically less likely to get a severe case of Covid-19
Professor Monica Gandhi, San Francisco General Hospital.
No mask is perfect
Wearing one might not prevent you from getting infected
But it might be the difference between a case of Covid-19 that sends you to the hospital and a case so mild you don’t even realize you’re infected.
Masks Do More Than Protect Others During COVID-19: Reducing the Inoculum of SARS-CoV-2 to Protect the Wearer (Journal of General Internal Medicine)
Universal masking reduces the “inoculum”
Leading to more mild and asymptomatic infection manifestations
Masks, depending on type, filter out the majority of viral particles, but not all
Viral inoculum and severity of disease (LD50)
Rising rates of asymptomatic infection with population-level masking
Increased with mask wearing, decreased where few masks are worn
So, more asymptomatic infections
Greater community-level immunity and slower spread
Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach (Annals of Internal Medicine)
The point is not that some particles can penetrate but that some particles are stopped
Every virus-laden particle retained in a mask is not available to hang in the air as an aerosol or fall to a surface to be later picked up by touch.
Cloth can block droplets and aerosols, and layers add efficiency.
Immunity and immunopathology to viruses: what decides the outcome? (Nature, Reviews Immunology)
The outcome of host–viral interactions depend on
Dose and route of infection
Viral virulence properties
Several host factors that mainly involve innate and adaptive immunity
If the exposure dose is very high, the immune response can become overwhelmed.
If the initial dose of the virus is small, the immune system is able to contain the virus with less drastic measures.
If this happens, fewer symptoms, if any
A simple method of estimating fifty per cent end points, (American Journal of Hygiene, 1938)
Viral dose being related to disease severity
Validation of the Wild-type Influenza A Human Challenge Model H1N1pdMIST: An A(H1N1)pdm09 Dose-Finding Investigational New Drug Study (Clinical Infectious Diseases)
Clinical symptoms of influenza occurred at all doses (Table 1), but were most prevalent at 106 and 107 TCID (tissue culture infectious dose)
Higher viral doses, the more sick people became
Simple Respiratory Protection—Evaluation of the Filtration Performance of Cloth Masks and Common Fabric Materials Against 20–1000 nm Size Particles, (The Annals of Occupational Hygiene)
Masks increase the rate of asymptomatic cases, (Annals of Internal Medicine)
COVID-19: in the footsteps of Ernest Shackleton, (MBJ, Thorax)
Cases at seafood plant cause spike in Oregon COVID numbers (Pacific Seafoods)
Releases Covid-19 Test Results at Northwest Arkansas Facilities (Tyson)
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