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ENT Manifestations of Migraine 28: Lifelong Headache and Dizziness
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This patient has a lifelong history of headache and dizziness from childhood. Symptoms became continuous decades ago but received little attention from physicians. She has had a dramatic response to low-dose nortriptyline. Tricyclic antidepressants have many possible mechanisms of action in migraine patients; they are serotonergic, are medium potency calcium and sodium channel blockers, are mildly antihistaminic and are anticholinergic. They are also very well tolerated in seniors when used at low doses.
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