How Apperent Volume of Distribution can be MORE than Total Fluid Volume in Body? Pharmacokinetics

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How Volume of Distribution Can Be More Than Total Fluid Volume In The Body?
Some drugs accumulate in deeper tissues, because of which their plasma concentration falls drastically. So when you calculate the apparent volume of distribution using that low concentration in plasma, you get a higher number for volume. This number can be higher than the total fluid volume in the body. This is because it is a calculated volume. Or in other words, it's an estimate. Not a real volume. Thus, the video also explains why its called an "apparent" volume.

Chapters:
00:00 Intro
00:43 Simple Model
04:00 In Human Body
05:36 Outro

Dr Vipul Navadiya
Nonstop Neuron
Medical Animation
Medical Animation Videos
Physiology

DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.