Nanopore detection of DNA methylation

In this simulation, a methylated strand of DNA goes through a nanopore that detects and maps the location of the methyl groups. A high number of methyl groups can be a sign of cancer.

Video by Aditya Sarathy

[JohnJones]

Methylation is the addition of 4 atoms (1 carbon 3 hydrogen) to a cytosine base on the inside of the DNA helix.

You've drawn a double helix with some sort of protein modification to the outside. wat.