Something weird happens when you add ANTIBIOTICS to BACTERIA under the microscope!

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In this video I added the beta-lactam antibiotic known as amoxycillin to a sample of bacteria!

Amoxycillin is a broad-spectrum antibiotic - usually given if you have a general infection.

Beta-lactams like amoxycillin interfere with the synthesis of the bacterial cell wall peptidoglycan - basically, they disrupt essential cellular functions that allow the bacteria to grow, spread and survive.

As such, it's not really surprising that I didn't really see less bacterial movement after I added amoxycillin to the bacteria sample -

Interesting - but consistent with the established science of beta-lactams and their antibacterial activity!

#shorts #science #stem #microscope #amoxycillin #antibiotics #bacteria #betalactam #chemistry #germs #biology
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And that's why you follow the directions on these - follow the whole schedule and don't stop early just because you feel better. Let it finish its work.

EaglesQuestions
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So just to clarify: he says that it slows the bacterial growth rate, but in fact amoxicillin is bactericidal, meaning it kills them. However, it only kills them when they are dividing, because it prevents them from making a new cell wall so when they try to divide they basically pop themselves. So you’d want to put some growth medium down and wait 20-30 minutes to catch a cell division!

tims
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Can you put the subtitles a little higher? because the title covers it up

Banespana
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As a health professional i can give some information that may be helpful for the video:

- There are bactericidal and bacteriostatic antibiotics, the first kills them, the latter stops them from growing in numbers;
- Amoxicillin, though a Bactericidal antibiotic, it acts mainly by inhibiting the cellular wall growth, this means, that the bacteria will die only after it tries to multiply (causing rupture and death), this may take some time to take action (probably like 30 minutes after contact);
- Not all bacteria can be killed by amoxicillin, it generally kill gram positive, mostly staphylococcus (though not a MRSA, which is a resistante staph) and streptococcus (causes a variety of infections.

So, in the sample you got in the video, there were probably more Gram Negatives and Anaerobic bacteria, generally resistant to amoxicillin.
I would recomend you try the same experiment with Antibacterial like Clindamycin and Ciprofloxacin or even a intravenously piperacilin+tazobactam, these can kill many types of bacteria. Furthermore, you want to keep observing the sample for about 30 minutes to see the action.

ArielAlvFal
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Capsules just pull apart, no need to cut it.

tianamarie
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as a medical student its very interesting seeing these things under the microscope! :) please more microscope videos sir

noellundstrom
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You don’t need to CUT the capsule. Just “unscrew” and open the two sides.

BitSmythe
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More likely the bacteria in your sample are gram negative, because they're rods. Amoxicillin is more effective for gram positive bacteria.

mdalie
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Please do a video on antibiotic resistance too.

jadeemperor
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That's why they ask you to take it for no less then 7 days or longer. They also suggest you take it around the same time everyday.

crownonpoint
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We really need a teacher like you.to let understand Biology or antanomy of humans😅..
You are good at this

wildyato
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It would be cool to do a side by side comparison of blood samples from that of a normal healthy person to a sample of a person with an autoimmune disease (if you’ve already done this I apologize lol, I’ve only JUST found your channel)

cicimichelle
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Instead of an antibiotic like amoxicillin you should have tested with an antibacterial eg Cefexime.
To work against bacteria you need antibacterials
To work against virus you need antivirals
And against fungus you need Antifungal meds.
Hope this helps someone in some way. Stay Happy and blessed all you lovely people out there.

Ps.. the capsule can be opened from the middle very easily. You don't need a blade to cut it open

dr.zishanalikhan
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It depends on the kind of bacteria, they may not be sensitive to beta lactam antibiotics and therefore not die. You always have first to assess the species of bacteria before you intervene with antibiotics

emachimia
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Wow! That’s very Insightful and interesting

onyekaigweze
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I like this channel. I find these things are really fascinating

Skyscraper
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Great interview 👍 good conversations to both sides 👍

aarondaniele
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You should go on to discuss bactericidal vs bacterostatic. You have a great introduction for it with this

borednurse
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Everything is our body and the system it provides, so lets not praise the medicines but praise the creator

Zkingaka
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Do more of this please 🙏🥺

Thank you 😊❤

kathyMP