What is Retinitis Pigmentosa?

David Birch, PhD, Scientific Director at the Retina Foundation of the Southwest, gives an overview of retinitis pigmentosa.

As Dr. Birch explains, retinitis pigmentosa is a group of rare, inherited ophthalmological disorders that affect the retina. Retinitis pigmentosa may be caused by mutations in any of approximately 150 genes. Inheritance can be autosomal dominant, autosomal recessive, or X-linked. The disease is characterized by progressive vision loss and the first sign is usually night blindness. As the condition progresses, affected individuals often develop mid-peripheral scotoma, and eventually total loss of peripheral vision as well as progressive central vision loss. Unfortunately, some retinitis pigmentosa patients will experience total vision loss.

It was recently announced that the first patients have been dosed in the phase 2/3 Sirius and Celeste clinical trials of investigational RNA therapy, QR-421a, for people with USH2A-mediated retinitis pigmentosa and Usher syndrome.

[brandondryer]

Half of my family struggles with this😢 I wish that someone out there could find a way to help

[Shanereacts]

Yeah I've had it for over 10 years

[heaven]

Fuck RP no one should ever have that shit it’s hell being around at night fearing if someone is gonna attack u or do something to u at night people really do take advantage when they know what u have surround yourself with people you know bless up my people🙏

[samgaming]

Many thanks for this. Other ocular conditions we see with RP include open angle glaucoma, cataracts, myopia and keratoconus.

[NahidHasan-xtoj]

Assalamu alaikum sir, I am RP patient, I want to do LASIK. I did pre LASIK test, mam said after seeing the report, I can do LASIK with RP disease but now I see 6/9 with glasses and after LASIK till 50-60 years of age 6/ I will see after 9th, power may come, sir, I am 22+, should I do LASIK now! Well, sir, will RP disease get better if I take gene therapy. Please tell me, sir?