Polyneuropathy

This video is part of the course Introduction to Neurology:

[jeetmann]

Thank you so much Dr Jensen. Been so confused with this concept, but you've explained it so clearly succinctly :)

[zSchreckensszene]

Polyneuropathy (B/L): diffuse dysfunction of peripheral nerves
- presentaiton:
-- Somatosensory: of the B/L distal limbs (longest nerves): introduce the most common syndromes: numbness ascends from toes to feet

--- progression:
---- 1. numbness starts from toes and begins to ascend
---- 2. numbness ascends to knees, and starts from finger tips
-- LMN: proximal limb (shoulders/thighs) weakness or loss of muscle stretch reflexes
-- Autonomic: orthostatic hypotension
- pathophysiology:
-- demyelinating: myelination is being removed
-- de-axonating: peripheral nerve axons are being injured
-- both:
- causes: genetic, idiopathic, autoimmune, metabolic, toxic
-- genetic: Charcot-marie-tooth syndrome: (some mutations cause demyelination, others axonal loss)
-- autoimmune: guillain-barree syndrome: demyelinating:
-- metabolic: diabetes melitus: blood

[hcwcars]

Thank you for this video it helped me understand better i must of been living with Polyneuropathy for over 10 years without knowing

[richardbeliveau]

The difference between upper and lower motor neuron?

[garfle]

What purpose does this serve if there isn't any possible remedies provided ?

[DaniellaSpizz]

Can poly neuropathy cause toes to twitch?

[lloydaguirre]

is it possible that it will start under the knee?

[pirginjo]

Is it always a case that spreads to hands?

[hamzakhan]

Didn't want to delete the old video huh? :P