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Systemic Lupus Erythematosus (SLE),PART 2, Clinical features- NEET ,USMLE ,University Examinations
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PART 1 Causes and pathology SLE :
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In this video , PART 2 , Lecture on clinical features of systemic lupus erythematous (SLE )
Time stamps
00:00 intro
00:17 Skin diseases
05:06 Joint disorders
06:45 Lupus Nephritis
11:58 CVS
12:30 Hematoxylin bodies
Please spread the word if you enjoyed the lecture
**Errors/misinterpretations
1) Nasolabial fold is marked Incorrect
2) Keratinocyte scaling is technically incorrectly explained, sorry for my misinterpretation, but the explanation given in this video was only aimed at helping a medical student retain the 3 important biopsy findings in discoid lupus erythematosus
Conceptual Explanation
Some concepts in this video
1) SLE in Skin / joints / Renal / CVS / bone marrow etc
2) Skin = Cutaneous Lupus
3) Renal = 6 types of nephritis : Lupus Nephritis
Minimal mesangial Lupus Nephritis
Mesangial proliferative Lupus Nephritis
Focal Lupus nephritis
Diffuse lupus nephritis
Membraneous Lupus Nephritis
Advanced sclerosing Lupus Nephritis
4 ) RHEUMATOID ARTHRITIS VS SLE = NoN erosion is the distinguishing Feature of SLE arthritis
5) CARPET TRACK SIGN : characteristic lesions are well-defined erythematous plaques with partially adherent scales entering a patulous follicle. When the scale is removed, its undersurface shows horny plugs that had occupied follicles. This is called the carpet tack or tintack sign.
6) HEMATOXYLIN BODIES : homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear material from an injured cell, along with autoantibodies and a limited amount of cytoplasm
7) LE CELL : (Lupus Erythematosus cell) is a neutrophil or macrophage that has phagocytized (engulfed) the denatured nuclear material of another cell.
8) Jaccoud arthropathy is a deforming non-erosive arthropathy characterized by ulnar deviation of the second to fifth fingers with metacarpophalangeal joint subluxation
lectures Based on
Robbins Pathological basis of disease
Harrison's Internal medicine
Suitable For University examinations , NEET , USMLE, AIIMS , JIPMER
Watch in 1.25/1.5x if You feel the lecture is slow 😉
If you enjoyed the video, please like , subscribe and share the vidoes ❤️
Please let me know of your feedbacks and suggestions in the comments section
And also any topic to be discussed
About me :
Thank you for watching the video and reading the description upto this area, I'm a 2nd year Medical student in Govt. Medical college manjeri ,kerala, india ,i hope you enjoyed and clicked subscribe ❤️
you are a great human being 💕
Disclaimer :
**Although i try my best to be as accurate as possible , errors may have crept in , please let me know in the comments section **
Please like and share the video ❤️ & subscribe to the channel
.
.
.
.
.
.
.
.
#SLE #Pathology #Harrison #Robbins #malayalam #Medical lectures #kuhs #keralaUniversityofhealth sciences #mbbs #medicolife #manjeri #cmc #Neet #neetpg #Aiims #aiimspg #medicallecture #pathogenesis #apoptosis #Etiology #simple explanation #concepts #clinical features
#lupusnephritis #nephritis
join for downloading notes in PDF for free😍
In this video , PART 2 , Lecture on clinical features of systemic lupus erythematous (SLE )
Time stamps
00:00 intro
00:17 Skin diseases
05:06 Joint disorders
06:45 Lupus Nephritis
11:58 CVS
12:30 Hematoxylin bodies
Please spread the word if you enjoyed the lecture
**Errors/misinterpretations
1) Nasolabial fold is marked Incorrect
2) Keratinocyte scaling is technically incorrectly explained, sorry for my misinterpretation, but the explanation given in this video was only aimed at helping a medical student retain the 3 important biopsy findings in discoid lupus erythematosus
Conceptual Explanation
Some concepts in this video
1) SLE in Skin / joints / Renal / CVS / bone marrow etc
2) Skin = Cutaneous Lupus
3) Renal = 6 types of nephritis : Lupus Nephritis
Minimal mesangial Lupus Nephritis
Mesangial proliferative Lupus Nephritis
Focal Lupus nephritis
Diffuse lupus nephritis
Membraneous Lupus Nephritis
Advanced sclerosing Lupus Nephritis
4 ) RHEUMATOID ARTHRITIS VS SLE = NoN erosion is the distinguishing Feature of SLE arthritis
5) CARPET TRACK SIGN : characteristic lesions are well-defined erythematous plaques with partially adherent scales entering a patulous follicle. When the scale is removed, its undersurface shows horny plugs that had occupied follicles. This is called the carpet tack or tintack sign.
6) HEMATOXYLIN BODIES : homogeneous, basophilic particle, easily stainable with hematoxylin. It consists of degraded nuclear material from an injured cell, along with autoantibodies and a limited amount of cytoplasm
7) LE CELL : (Lupus Erythematosus cell) is a neutrophil or macrophage that has phagocytized (engulfed) the denatured nuclear material of another cell.
8) Jaccoud arthropathy is a deforming non-erosive arthropathy characterized by ulnar deviation of the second to fifth fingers with metacarpophalangeal joint subluxation
lectures Based on
Robbins Pathological basis of disease
Harrison's Internal medicine
Suitable For University examinations , NEET , USMLE, AIIMS , JIPMER
Watch in 1.25/1.5x if You feel the lecture is slow 😉
If you enjoyed the video, please like , subscribe and share the vidoes ❤️
Please let me know of your feedbacks and suggestions in the comments section
And also any topic to be discussed
About me :
Thank you for watching the video and reading the description upto this area, I'm a 2nd year Medical student in Govt. Medical college manjeri ,kerala, india ,i hope you enjoyed and clicked subscribe ❤️
you are a great human being 💕
Disclaimer :
**Although i try my best to be as accurate as possible , errors may have crept in , please let me know in the comments section **
Please like and share the video ❤️ & subscribe to the channel
.
.
.
.
.
.
.
.
#SLE #Pathology #Harrison #Robbins #malayalam #Medical lectures #kuhs #keralaUniversityofhealth sciences #mbbs #medicolife #manjeri #cmc #Neet #neetpg #Aiims #aiimspg #medicallecture #pathogenesis #apoptosis #Etiology #simple explanation #concepts #clinical features
#lupusnephritis #nephritis
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