Choosing Between SN1 SN2 E1 E2 Reactions

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This video walks you through a four-part checklist that can be used to determine whether a given reaction will proceed via an SN1 SN2 E1 or E2 reaction mechanism and also which product molecules will be formed. You’ll learn how to analyze the degree of substitution of the starting reactant, the strength of the attacking nucleophile or base, the type of solvent, as well as the strength of the leaving group.

Additionally, you’ll learn about the notable exception of the big bulky base and why it forms the Hofmann product. You’ll also learn why the presence of heat in a reaction favors elimination, as explained by a reaction coordinate energy diagram. Finally, you’ll see me work through a few examples so that you can apply what you’ve learned to real test questions.

↪ Links & Resources Mentioned In This Video ↩

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⏱ In this video:
[0:38] The Four Part Checklist
[0:55] Alkyl Halide
[3:33] Attacker
[6:12] Solvent
[8:23] Leaving Group
[10:15] Practice Problems

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