Vaccine sequence Retrieval & Structural Analysis | Vaccine Design Step 1| Lec 53lDr. Muhammad Naveed

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Vaccine Desing STEP 1: Sequence Retrieval and Structural Analysis
Physiochemical analysis (ExPAsy Portparam)
Secondary structure prediction(PSIPRED tool)
Disulfide bonding prediction (DiANNA1.1 tool)
Tertiary structure prediction (trRosetta)
NCBI Database/UniProtKB is used to retrieve the M-protein of Severe acute respiratory syndrome beta coronavirus using the accession number MT520466.

About Dr. Muhammad Naveed
(Associate Professor, Biotechnology, University of Central Punjab, Lahore)
Dr. Muhammad Naveed obtained a Ph.D. degree in Biotechnology (Genomics & Bioinformatics) from Quaid-e-Azam University, Islamabad with distinction. He has won Ph.D. indigenous & IRSIP scholarships from HEC. He has done Pre-Doc research at the University of Ghent, Belgium. HEC awarded best Ph.D. (IRSIP) Scholar of the year 2013 & QAU honored him as “Distinguished Alumni” in 2017. He is doing research projects in Bioinformatics & Molecular Biotechnology. He has supervised 45 MSc., 40 MPhil. & 01 PhD. He has published 74 Research articles with 253 impact factor and 700 citations, 01 book, and 03 book chapters. He has been awarded distinguished “Researcher of the Years (2016, 2018 & 2019)” by UoG and UCP.
#VaccineDesign #VaccineSequenceRetrieval #StructuralAnalysis
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Dr. Naveed is a blessing for us, especially for bioinformatics learning aspirants

usman
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Sir ek doubt tha, hum pyrx tool se ek protein or ligand ki docking krte h or xyz center hum suppose 8, 9, 30 rakhte h or binding affinity -10kcal/mol aate h or phir hum xyz ki value same rakhte h same ligand or protein ke liye to binding affinity -15kcal/mol aate h aesa kyu hora h sir ?

surajjoshi
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Asslam o Alikum sir! agr hmari target protein mn koi bhi Disulfide bond na aye (DIANNA) toh iska vaccine designs mn koi issue toh ni ha?

ihteshamharoon
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DiANNA software K result Ni a rahe sir kindly help

sanadilbar
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AoA Sir plz can you tell me about the tool to check the tolerance and differentiation between self and non self.

quranpak
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Dear Sir..
Thank you so much...
sir, after completion of this important series..Please make a video on how to draw high resolution figures/diagrams for life sciences/biology research/review articles....
Freely and easily!

Thank you😇

Anil-Behera
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Assalamualaikum sir
Sir M Protein ka accession number clear ni hai please like k share kro thanks

romanakbar
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Sir kindly y btein k hm results kesy interpret kr skty hn jesy k apny Expasy use kiya properties ki prediction k liy to knsi proteins best candidate hngi for vaccine hydrophobic y hydrophilic???? Unki PI value kitni honi chae?

fizzafarooq
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Sir kiya hEC ne apni new policy bs leading to phd start Ki hai?

Sad-kdib
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Sir, psipred py protein sequence add krny k bd arha h invalid characters

Snaps
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Sir is there any difference between drug design and vaccine design ?

ismail
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Anyone who can help me . For vaccine production?

Snaps