Coronavirus Update 121: Johnson and Johnson Vaccine - Efficacy and Safety vs. Pfizer & Moderna

Professor Roger Seheult, MD explains the Johnson and Johnson / Janssen Pharmaceuticals vaccine candidate for COVID 19. Dr. Seheult illustrates how the Johnson & Johnson adenovirus vaccine works, the efficacy/safety (based on preliminary data), and how the vaccine compares to the Moderna vaccine and the Pfizer BioNTech vaccine. (This video was recorded on February 4, 2021).

He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

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[wt.]

J&J vaccine development trials were done at different time than Pizfer and Modnerna. Results would be different. J&J vaccine was developed utilizing traditional methodology that is in place for over 50 years. This is same methodology used to develop the Ebola virus vaccine- very successful. I would go would the J&J vaccine.

[Meltiqueful]

For me, the main question is: have they done enough testing on people with autoimmune disease?

[mireyamorgan]

I took the Johnson & Johnson vaccine it’s been 24 hrs already and I feel great no soar arm or side effects Thank The LORD 🙏🏼

[Mmmyess]

The question at the end should have been: "If a person has all four vaccines available at the time, which would you recommend s/he get?"

[joanngutierrez]

I got the Johnson Johnson at Kroger's Monday this is my second day and I am okay so far thank God I pray everyday I know I will be okay👍

[justachipn]

I just got JJ today at my VA 😁 It's been 10hrs and not even a sore arm... all's good !!! 👍

[TravelingStageManager]

Got my J&J and after 2 days no side effects except a slightly sore arm at injection site. But not even as bad a past flu shots. I am very grateful to have the 1 & done.

[lolaras]

@6:18 i thought our goal was to demolish the virus for good, not just prevent heavy or severe symptoms, since it can continue to mutate. If not, and i could be mistaken, then this could become like another almost 'seasonal flu' or 'cold' that we will always have around?

[joyfisher]

Thanks for updating us. Praying for you both & all health care workers

[sonianieves]

My 81 yr old mom and I 62 ..had the jensen vaccine two weeks ago..no side effects..

[mv]

what i really want to know is how long does this DNA stays active producing MRNA in your body?

[pennysue]

I got the J & J vaccine yesterday at 10am...last night while sleeping I had the chills pretty bad for about 2 hours, and this morning a bad headache.

[ElementalGeneral]

I don't know much... but I know the mitochondria is the powerhouse of the cell.

[tonytango]

Thank you so much for using diagrams with a black background and white or light coloured text and graphics. I am severely visually impaired and cannot view anything with a white background without 10 times longer trying to figure things out.

[cronn]

My wife and I received J&J vaccine 2 weeks ago and other than a stuffy nose for a few hours, we experienced no problems whatsoever. Very happy we got the shot.

[mariaclaraarcheta]

Im on my 10th day after i was Janssen vaccinated. So far so good! No discomfort whatsoever. Thank God! 🙏

[briangriffiths]

My 84 year old parents had the Oxford Astrazeneca vaccine earlier this week. No side effects at all.

[pamsmith]

I got this vaccine. I got a migraine that lasted 12 hrs even with meds, had chills & body aches but only for about 4 to 6 hrs. I don’t normally have side affects from other vaccines. I also had no soreness in my arm afterward.

[Tiffanyslocjewels]

Which one is best for people with severe allergies? That’s what I’m most concerned about

[debrapierce]

I have a question - how do the vaccines affect people who are rh- blood type? My understanding is the the outer protein layer is missing from an rh- blood type person. Also, since this is essentially made from some type of human dna or lipids or whatever then can the person with rh- blood type be negatively affected? Could that have been what happened with the Dr. that died after having the vaccine? If you think about why a woman has to get a Rhogam shot to protect the baby from the body turning on it then could his thrombocytopenia have been induced this way as well? I realize that there is only a small percentage of the population with Rh- blood type. Are these things to consider before getting the vaccine? Because I believe in the race to get this out that the good of the many may have outweighed the good of the few on this one. I ask these things because I have tried researching to find an answer and have found nothing. And I do not have the medical knowledge necessary to know whether my concerns are valid. Dr. Seheult, if you could respond, I would greatly value your opinion as I am one of the Rh- population.