Cleo Abram: Metformin, the Anti-Aging Drug… or is it?

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References [Copy and Paste DOI into Search]
[1] doi: 10.1111/dom.12354
[2] doi: 10.1093/ije/dyac200

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#metformin #antiaging #hugeiftrue

[zhilahaghbin]

Thanks Nick, would you cover Rapamycin as well, how to take it? its side effects, studies on longevity or age reversal. great content as always.

[lukenukem]

Man this channel is good for helping people to brush up on critical thinking and analyzing data in general. Can apply these skills to any field. Salute to da Doctor 🫡 👨‍⚕️

[eilaollinheimo]

I got metformin for pre diabetes and had to stop it in few months. Dizziness, nausea, chronic cough, headaches, diarrhea. I was unable to do much ( fatigue adding to it) and working became near impossible. I will never touch that drug again

[DIABETESHEALTHS]

You should have started to Y Axis from 0.9 or so.

[dazone]

Could we look at health span as well as lifespan please

[relativityboy]

I'm in the TRIIM-X trial and lemme tell-yah. Metformin does not make one feel awesome, even when on all the other stuff lol.

[santolamari]

i would love to hear your thoughts on Berbrine...which apparently works better than Metformin. :)

[DingusCirc]

There are tons and tons of stuidies out there showing the many benefits of Metformin. Not sure why none of those were mentioned.

[MarcMallary]

Berberine is supposed to work similar to metformin and is natural.

[_negentropy_]

I’m not clear on how metformin is expected to “push back death by age-related diseases” other than type 2 diabetes? Do they already understand its mechanistic contribution to longer life-span in that very specific population?

[lucaslouzada]

You said it’s not necessarily the researchers’ fault, but the simple fact of him getting so excited with the media attention, as well as all this talk of repurposing based on a study that goes against randomized control trials, shows a handful of redflags…

[joeboxter]

People have been claiming that for a long while. It doesn't work.

[noahlovotti]

Metformin is done. We must move past it and continue the growing longevity research.

[TheCookiecupcakes]

The woman in this vid is so incredibly beautiful. She always makes me stop and pause when I come across her content.

[jmc]

One group of researchers has been looking at it for yrs as part of a cure or prevention for aging and or life extension. Watched a good doc video on it a few yrs ago and read some articles.

[roqclimber]

I'm the chart, Prevalence of Chronic Conditions as a Function of Age, the point of Divergence is where Diabetics Begin dying of Cancer and Heart Disease.

[HuFlungDung]

Studies presented as science are really not science at all. They just pose a question and whether it merits further investigation as to the actual underlying biologic function. Don't base your living choices on 'conclusions' from studies unless you want to be a statistic.

[HSLSFirst]

Working out hard doing cardio and strength training 6 days a week makes me feel good and healthy. That is the only supplement I trust. No other snake oil for me.

[davidcolin]

I LOVE your videos! I’m wondering if you’ve ever thought about doing a video on over feeding studies where the subjects do not gain an appreciable amount of weight? And how that comports with the obesity epidemic.

[myscreenurs]

Longevity is not a pill people. It's a skill