Introduction to Buffer System || Regulation of pH || Acid Base Balance || Buffers in Biochemistry

Buffer system for the acid base balance and regulation of pH - This video is on the introduction to Acids, Bases, Buffers, physiological pH of blood and different types of extracellular buffer and intra cellular buffer which are first line of defense for the regulation of pH.
Acids, Bases and buffers - 00:24 minutes
Normal pH of the body fluids - 01:45 minutes
Why maintenance of a pH is important - 02:28 minutes
Fixed acids or Non volatile acids - 03:25 minutes
Volatile acids - 03:50 minutes
Metabolic Sources Of Bases - 04:05 minutes
Mechanism for the regulation of pH - 04:40 minutes
Buffering Capacity - 06:40 minutes
pKa - 06:48 minutes
Intracellular and Extracellular buffer - 07:42 minutes
Bicarbonate Buffer system - 08:56 minutes
Mechanism of Bicarbonate buffer - 09:43 minutes
Phosphate buffer system - 12:47 minutes
Mechanism of phosphate buffer - 13:08 minutes
Protein buffer - 15:03 minutes
Hemoglobin buffer - 16:12 minutes
Mechanism of hemoglobin buffer - 17:14 minutes
Chloride Shift - 18:28 minutes
NEET PG Biochemistry MCQs - 21:03 minutes

ACIDS, BASES AND BUFFERS
An acid is defined as a substance that releases protons or hydrogen ions (H+), e.g. hydrochloric acid (HCI), carbonic acid (H2CO3).
base is a substance that accepts protons or hydrogen ions, e.g. bicarbonate ion (HCO3–), and HPO4– –

Buffer is a solution of weak acid and its corresponding salt which resists a change in pH when a small amount of acid or base is added to it.
By buffering mechanism a strong acid (or base) is replaced by a weaker one.

Normal pH Of The Body Fluids

The normal pH of arterial blood is 7.4
pH of venous blood and interstitial fluids is about 7.35
The pH of blood is maintained within a remarkable constant level of 7.35 to 7.45.
Regulatory Mechanisms to maintain normal Blood pH

Buffer mechanism: First line of defense
The respiratory mechanism: Second line of defense
Renal mechanism: Third line of defense.
Blood Buffer

Buffer System Extracellular buffer Intracellularbuffer

Bicarbonate NaHCO3/ H2CO3 KHCO3/H2CO3

Phosphate Na2HPO4/NaH2PO4 K2HPO4/KH2PO4

Protein Na Protein/H. Protein KHb/H.Hb
KHbO2/H.HbO2

#biochemistrybasicsbydramit #pHregulation #buffersystem #acidbasebalance #NEETPG #NEETPGbiochemistry #USMLE

[tagedumi]

Short, crisp and on to the point. Just what I was looking for.
Thank you for simplifying the topic sir.

[raghadbarjas]

This was so helpful for Thank you so much may allah bless you

[anshudeo]

So so much thank you sir.
Was looking for this since the begining and finally understood the concept. ☺

[rajeevreddy]

Buffer is a Not a substance
NYC presentation and clearly explained

[vevyovi]

thank you very much it is the most detailed video which I encountred

[SultanaNazmun_Naim_]

Thank you sir... it's really helpful 👍

[subhashreemahalik]

thank you so much for making the things very easy.

[aseelmaher]

Thank you ...
I have a question
Does phosporic acid act as a buffer ?

[carafadaleeli]

please what is relationship between HP and potassium K ??

[rubeenagurung]

In bicarbonate buffer system can we use weak acid as carbonic acid and strong base salt as sodium bicarbonate??

[sarahgamaleldean]

Thanks sir...l will follow the other videos for you to get more and more informations...thank you again

[crazysiva]

Sir pdf format ah send panringala please🙏🏻

[adsrrdtz]

Thank 🙏 u soo much sir
Sir is there notes for ur lectures

[gulfwarveteran]

Thanks sir i understood the topic thoroughly

[prashantgupta]

Sir, please provide notes of all lecture video on the website 🙏🙏🙏🙏🙏🙏🙏 please sir

[arungaliyt]

**02.26 wrong explanation**
Increasing Of PH is “Acidosis” Decreasing of PH is “Alkalosis”

[muhammadshamsuddin]

Sir could you please share this lecture note? Please sir 😇 It was awesome lecture