Genome Editing and CRISPR | Breakthrough Junior Challenge 2020

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#breakthroughjuniorchallenge
This short video discusses genome editing and CRISPR. This is my Breakthrough Junior Challenge 2020 submission.
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It's nice to know that you can play a instrument, be athletic and be as smart as Einstein. Keep up the good work Antonio

mayam
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Really nice, love the animation. Great video, from a fellow competitor!! You did a good job...

anjolasworld
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Nice job. CRISPR is something I am really curious about. Last I read about it was that it's editing with it still inaccurate? Lots of unexpected mutations due to it missing the target?

PyMoondra
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hi, really cool video. Was working with it myself in the lab lately and had to do some deeper research about it. Quite astonishing that we could just copy one of the most precious and valuable techniques in the next 100 years by looking at some bacteria. I like your videos and animations and you speak in a tone which makes me want to listen. Cheers from Vienna

philippthill
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Great video!!! I couldn't quite understand most of this stuff in school.

KatyMac
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Love the video!
Keep up the great work!!

antoneberhardt
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As commented before, you're really good at making animated videos. I'm a biotechnologist and I noticed a general error made by anyone who doesn't know already how DNA works. Size, shape of a vegetables (you put the tomato, which is perfect example) aren't determined by a single gene. These are called QTL (Quantitative Trait Locus), because there's not a single gene responsible for this trait: the additional effect of an unfixed number of genes determine this one. With CRISPR/Cas9 you could design a sgRNA targeting a specific region of the genome, but also in one traitment multiple Cas9 and multiple sgRNA. Problem is that as much as you increase the number of sgRNAs (and Cas9) introducted into the cells, the lower are the possibilities that your Cas9 will really cut the DNA in every targeted point (possibilities become lower when you're trying to replace the original DNA with a chosen fragment). So actually you couldn't edit a QTL in a one-shot Crispr/Cas9 experiment without doing breeding and selection methods.
p.s. you're still a kid, keep training. Good luck!

freeweedall