Top 10 Grey's Anatomy Cast Feuds

"Grey's Anatomy" is full of feuds and drama, but in front of and behind the camera. Our countdown includes Ellen Pompeo vs. Katherine Heigl, Eric Dane vs. Shonda Rhimes, Kate Walsh vs. Everyone, and more! Which "Grey's" feud shocked YOU the most? Let us know in the comments!

Watch more great "Grey's" videos here:

Have Your Idea Become A Video!

Subscribe for more great content!

MsMojo is a leading producer of reference online video content of Top 10 Lists, Origins, Biographies, Commentary and more on Pop Culture, Celebrity, Movies, Music, TV, Film, Video Games, Politics, News, Comics, Superheroes. Your trusted authority on ranking Pop Culture.

#GreysAnatomy #Greys #Feuds #Drama #TV

[April]

Katherine Heigl was right about not getting good material to receive an Emmy nomination, though. And she was right to stand up for T.R. against Isaiah’s blatant homophobia. That man is gross.

[GeraldoLM]

Katherine was on this list 3 times, and y'all think that she's a horrible person? and didn't get along with her co-stars? While her feud with Isaiah was to defend her best friend after he got called a slur, the other remained silent until she spoke up. And she dropped out of the Emmy's because she felt her character was poorly written and that she didn't deserve it while someone else's did (and it's a valid reason considering how bad her storyline was). Dempsey, Dane, Chambers, and Night were close to her.
If she were a man, y'all would act differently and defend her to death. And Shonda still gives Ellen a show actually says a lot about her.

[Xxxha]

Sandra Oh seems drama-free. I love her!

[katekatkitkat]

You can’t help but wonder how the show would have been different if T.R. Night was able come out on his terms, instead of being forced out. And maybe using it as inspiration for his character on the show 🤔

[jacie]

Katherine Heigl stood up for what's right, despite it going against majority opinion...doesn't make her a horrible person. Quite the opposite, makes her strong, badass and unique. People who disagree, are people who can't stand strength because it puts a spotlight on their weakness, js

[kyndalblackwell]

6:31 I really don’t understand how the rest of the Grey’s Anatomy cast could be so jealous and childish about Kate Walsh getting the opportunity to do a spin off instead of supporting her for the great opportunity she was given for her success in Grey’s Anatomy. She can’t really help that she’s the one they chose to give the spin off to and the rest of the cast wasn’t and yeah that sucks but that shouldn’t give them the reason to discredit all the great work she’d done to get to receive the opportunity to be the lead actress of a spin off. I just don’t understand how they wouldn’t be happy for her and just congratulate her on the opportunity that she was given even if they were upset they weren’t given the opportunity they still should have just put on a good face and been kind and respectful of her opportunity and of the writers and producers decisions.

[fantasyprincessgirl]

What about Isaiah Washington and Patrick Dempsey? I feel like they should have been at number one because of a fight that involved a homophobic slur and physical blows that cause Isaiah to be fired from Greys Anatomy!

[sadem]

Ellen Pompeo is so full of herself now. Her power as the lead actor in Grey's has gone to her head.

[julea]

Lexie (Actress Chyler Leigh) had a horrific death when the plane crashed. Usually people who worked with her say that she is a very sweet person?!

[tudorjason]

With all these feuds, I guess this is the toxic environment that Ellen Pompeo has mentioned in the past.

[kirramcdowell]

Can we have Christina back please. Her snark made the whole show for me. I also loved Addie. Dunno, Meredith is boring to me

[ashleyhannigan]

Sorry, Ellen. If you are on this list multiple times and you can't seem to get along with anyone; you are the problem!

[lonellfletcher]

How has this show lasted so long with so much toxicity?

[kurdtjohn]

Out of every Grey's Anatomy character, I think T.R Knight aged the most gracefully haha

[jayngb]

I love how Katherine Heigl and Ellen Pompeo appeared on this list multiple times lmao. I really loved Isaiah Washington’s character and his acting, it was sad to see him go but he shouldn’t have said those things about TR Knight.

[HatsAndFacts]

Katherine Heigl made a very successful acting career and is the third richest actor in Greys the only reason Ellen said that is she couldn’t become as successful as that level of success for she isn’t as good of an actor.

[maggierex]

It's amazing how much of the fued fueled the on screen dynamics

[glogler]

Patrick Dempsey was responsible for a lot of drama on set. Why wasn't he on this list?

[ilphi]

I swear if I see Sandra Oh vs. Ellen Pompeo here I can't not handle it
I can't watch Glee anymore after all the backscreen drama and Lea Michele and all the deaths

[reaganquinley]

Isiah saying on Twitter that he stands by his words and actions to this day when is words were the F slur and his actions were a physical altercation with a coworker… gross