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Chemobrain, Steroid Rage and Other Ways Transplant Meds Affect Your Brain
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Summary: Chemobrain and steroid rage are common side effects of drugs used during a stem cell transplant. This presentation reviews the causes and symptoms of these problems as well as the prospects for full recovery from them.
Presenter: Adrienne Mishkin MD, MPH, MS, NewYork-Presbyterian/Columbia University Irving Medical Center
To read the highlights, go to:
Highlights:
Chemobrain can be caused by any type of chemotherapy. It can start weeks or months after chemotherapy. It does not usually get worse and can improve with time.
There are a lot of psychiatric side effects of steroids used to treat graft-versus-host disease (GVHD). The most common ones are feeling anxious, agitated, irritable or moody. About a third of patients on steroids will have mild to moderate psychiatric effects.
Knowing what to expect can be helpful for people at risk for chemobrain and steroid side effects. Family caregivers can help by reporting symptoms of these issues to the patient’s healthcare team.
April 2023, Part of the Virtual Celebrating a Second Chance at Life Survivorship Symposium
Presentation is 20 minutes long followed by 34 minutes of Q & A.
Key Points:
(02:14): Patients with chemobrain often report feeling “delayed” and not as focused as they used to be. It can take longer to think of what they want to say and they may have short-term memory problems.
(02:39): Chemobrain is less severe than dementia.
(04:17): Chemotherapy can damage neurons in the brain, which can affect the speed with which one can do certain tasks, and the hippocampus, where memory is stored.
(06:50): Chemobrain can be treated with cognitive retraining therapy.
(10:09): When steroids are stopped or significantly reduced, most people feel low, tired and/or sleepy. Some will still have anxiety, mania, or confusion.
(10:35): About 40% of patients who are treated with steroids will have some kind of psychiatric side effect in the first week after taking steroids. Almost two-thirds will have symptoms within two weeks, and most within six weeks.
(11:31): The psychiatric side effects of steroids can last up to two months after the last dose of steroids.
(11:57): Steroids can cause exaggerated emotions and trouble sleeping.
(13:06): Steroid side effects may be lessened by changing the dose or switching to other medications.
(14:55): Several antibiotics, antivirals and antifungals can cause psychiatric side effects, especially Voriconazole (Vfend®)
Meet the speaker:
WHO WE ARE: BMT InfoNet is dedicated to providing patients and their loved ones with emotional support and high quality, easy-to-understand information about blood stem cell transplants (bone marrow, peripheral blood and cord blood) and other cellular therapies. Whether you are just beginning your transplant or cellular therapy journey, or learning to manage the joys and challenges of survivorship,
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Presenter: Adrienne Mishkin MD, MPH, MS, NewYork-Presbyterian/Columbia University Irving Medical Center
To read the highlights, go to:
Highlights:
Chemobrain can be caused by any type of chemotherapy. It can start weeks or months after chemotherapy. It does not usually get worse and can improve with time.
There are a lot of psychiatric side effects of steroids used to treat graft-versus-host disease (GVHD). The most common ones are feeling anxious, agitated, irritable or moody. About a third of patients on steroids will have mild to moderate psychiatric effects.
Knowing what to expect can be helpful for people at risk for chemobrain and steroid side effects. Family caregivers can help by reporting symptoms of these issues to the patient’s healthcare team.
April 2023, Part of the Virtual Celebrating a Second Chance at Life Survivorship Symposium
Presentation is 20 minutes long followed by 34 minutes of Q & A.
Key Points:
(02:14): Patients with chemobrain often report feeling “delayed” and not as focused as they used to be. It can take longer to think of what they want to say and they may have short-term memory problems.
(02:39): Chemobrain is less severe than dementia.
(04:17): Chemotherapy can damage neurons in the brain, which can affect the speed with which one can do certain tasks, and the hippocampus, where memory is stored.
(06:50): Chemobrain can be treated with cognitive retraining therapy.
(10:09): When steroids are stopped or significantly reduced, most people feel low, tired and/or sleepy. Some will still have anxiety, mania, or confusion.
(10:35): About 40% of patients who are treated with steroids will have some kind of psychiatric side effect in the first week after taking steroids. Almost two-thirds will have symptoms within two weeks, and most within six weeks.
(11:31): The psychiatric side effects of steroids can last up to two months after the last dose of steroids.
(11:57): Steroids can cause exaggerated emotions and trouble sleeping.
(13:06): Steroid side effects may be lessened by changing the dose or switching to other medications.
(14:55): Several antibiotics, antivirals and antifungals can cause psychiatric side effects, especially Voriconazole (Vfend®)
Meet the speaker:
WHO WE ARE: BMT InfoNet is dedicated to providing patients and their loved ones with emotional support and high quality, easy-to-understand information about blood stem cell transplants (bone marrow, peripheral blood and cord blood) and other cellular therapies. Whether you are just beginning your transplant or cellular therapy journey, or learning to manage the joys and challenges of survivorship,
VISIT US ON SOCIAL MEDIA:
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