Lecture 11 The Neurobiology of Addiction The Reward Pathway

Description of the brain's reward system, also known as the dopamine reward system with particular focus on the effects of drugs of abuse on reward processes and responses to reward cues. I discuss the reward prediction error signal and incentive salience and the role of executive functions or working memory in regulating our response to natural versus artificial rewards. Finally I discuss the role of stress as a cause of drug abuse and social networks as a buffer against drug abuse.

[blizzard]

This helped a lot, I'm doing my masters in substance use counseling and your definitions/explanations were a bit better than parts of my textbook, thanks!

[Vogliosololitigare]

This lecture is great, thank you. I know I’m late, but I was wondering if there was a bibliography to consult regarding this lecture? Or perhaps some suggested books? Thanks in advance

[quevinjimenez]

This question might too late in time, but is there any way I could get the name of the research done on genetics? I would really like to read it.

[emilynell]

Been completely mystified by the teaching I've had on this & you've really cleared it up, thank you :)

[stephenrblv]

10:00 is about important a concept to fully understand as asking the question does God exist. Mind-Blown

[angelacollins]

Can your brains reward system repair itself after quitting heavy marijuana use?

[markg]

Thankyou. The audio kept on dropping out and it was hard to follow. just as a suggestion please try to fix the audio glitches

[FoxyLobo]

I'm very interested to know what that genetic alteration is which was heritable to grand-offspring resulting in decreased preference for cocaine administration.. thanks for the interesting video

[threethrushes]

Doesn't 'consummatory' mean that once the needs have been met (=consummated), the initial drive dissipates?

[XyZ-debe]

Thanks a lot, it helped me a lot for my study (psychology

[darrriuskotey]

Is incentive salience part of the dopamine hypothesis?

[jloren]

The rat thing may be more direct form of evolution instead of a passed down mutation. Maybe the drug kills many sperm, leaving the survivors resistant? There must be something like this, since Koalas are a thing? I know the leaves and koalas have been in a long dance of an arms race but you get my point.

[stutijoshi]

Loved your lecture, so simple and on point. Can you please give references for neurobiology of addiction?

[williamharrisonjr]

if any of the neurological pathways are blocked from opening and flowing properly the client develops addiction due to the fact that the client uses more and more substances to try to force the neurological pathway to open through more chemicals and substances therefore the pathways in the brain must be unblocked and opened for normal flow of proper order to prevent the build up of blockage of the brains pathways once the client is off the substances and normal functions in the brains pathways return the client can no longer no matter what go back to those substances causing addiction

[ssnypzzct]

Sort your audio out bro 😂bloody hell man

[stephenrblv]

15:45 is it from stress? or is it from technology which is replacing most of the healthy motivators our genetic make-up needs to remain in a balanced state? I think this disruption of the routine IS the stress. Idle minds and Devils Workshop etc. People simply have too much idle time now and are filling the void with sports, gossip, mundane music, trivia, scrolling and organic compounds. Go home tonight and begin cleaning your living space by hand. Dusting wiping sweeping. Doesn't leave much time for coping and is far more rewarding. That sort of activity is congruent with our genetics. Asking Google is not. That is akin to a cocaine hit. Not congruent with who we are. This condition is STRESS.

[benjaminrojas]

So I see my sister and Christina and her kids they're trying to set me up so if you do the math on the conversion and the stream that they created we had stress social context and genetics Shoji and their Auto dictation is genetics SC is going to be social context so that's the Snapchat Instagram that's them hacking in your advice and then your stress they sit there and they haven't algorithm for your text messages to see who stressed out and he's not stressed out and then the MB on the string and has nothing to do with me it's one that they created it's going to be marketing bags brand of manipulation because they always use different color bag for the drugs that they use and every time she comes here she always advertises the color of the bags so basically that's what she's doing is she's creating a marketing campaign for methamphetamine in the drug Market maybe now they will tell the truth