Extrinsic Pathway of Apoptosis | FAS Ligand Mediated

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In this video the second pathway for extrinsic apoptosis have been discussed. This pathway is mediated via FAS Ligand and FAS Receptor.
The fas receptor (First apoptosis signal) – (also known as Apo-1 or CD95) is a transmembrane protein of the TNF family which binds the Fas ligand (FasL). The interaction between Fas and FasL results in the formation of the death-inducing signaling complex (DISC), which contains the FADD, caspase-8 and caspase-10. In some types of cells (type I), processed caspase-8 directly activates other members of the caspase family, and triggers the execution of apoptosis of the cell. In other types of cells (type II), the Fas-DISC starts a feedback loop that spirals into increasing release of proapoptotic factors from mitochondria and the amplified activation of caspase-8.
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My heart is literally jumping for joy watching how organized, color coded, and structured this video is. I love it. It makes me so happy. Thank you.

taruniipriya
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i dont know how to thank you for such a nice video
as always "short, informative, high yield"

mohammad.shokrolahi
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I am really overwhelmed after seeing your complete video on apoptosis, I am currently doing my masters in pharmacology and toxicology, no one could make the concepts so clear as you explained in this short video. Now I really want this question to be there in my exam. I really thank you for the wonderful video, you made it really really easy. Your efforts could be seen.

dhatrikareddy
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A fantastic, clear and concise introduction to this topic - thank you!!

animeloverXinuyasha
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Correction: CAD stands for Caspase Activated DNAse.
Awesome tutorial by the way.

Ashnaasweetgirl
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keep Working hard and smart....May ALLAH bless you for this kind of short informative video.

ishfaqahmadbaba
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Your videos are so awesome with all those colorful diagrams, it makes all those topics more easier and makes us eager to understand those. Thank you so much Sir❤️❤️💖

xrcc
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Just one little thing, I think the ligand and receptors are of 3 units (not 4) according to several sources, because they are involved in a step called trimerization. Other than that, it was a very nice video!! :D

tatsumiogawa
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U make the things so easy with the flow charts... Thanks alot!

poetxaastha
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It would really really help if you could include your sources in the description. Thank you for this video though. Amazingly explained.

shivasf
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in 4 minut video he teach us the whole concept that greats sir g

NoorKhan-pvex
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You are such a legend.. Thank you soo much!

janakignanan
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I appreciate it. You saved my assignment score.

dyieljc
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Finally!!! IVE BEEN SEARCHING THE WHOLE INTERNET AND THEY USES 10-15mins to explain this. I love this. Short n nice!:)

naileusmile
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you have ceased my caspase cascade, and I will now survive...

vishk
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That was beautiful... Thank you so much!!!😊😊😊

sanjithkarthikeyan
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you made my day! thank you for this amazing video <3

ngnhunghia
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Thank you for sharing and good explanation.☘️

hediyeklc
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very nice explaination....
stay blessed 👍👍👍

bhatsuriya
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thank you so much, jazaakallah, your picture is amazin!

dalilaafina