Antibody-Drug As A New Targeted Senolytic | Study Review By Modern Healthspan

In this video we review a study of a new drug which targets senescent cells. The drug is an antibody-drug conjugate which uses the antibody's ability to attach itself to specific proteins to find senescent cells then deposit a toxic payload into the cell and kill it.

Papers mentioned in this video
Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker

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[susanc.]

Excited to hear about this! If they can select only killing the bad senescent cells and leaving the good one alone then will be super!

[dhirajmeshram]

Thanks Richard wonderful to hear such development in targeted drug delivery ultimately leading to newer more efficient system in coming time 🙏

[rayyu]

Thank you for the great presentation, Richard. Get rid of unnecessary senescent cells always along with some good anti-aging effects.

[edwhite]

I would prefer fasting, exercise etc to clear up senescent cells

[ned]

Am I reading this right: the compound also killed 6% of non-senescent cells!? This is not nearly specific enough for in-vivo use.

[chadboomershine]

This will cost thousands per treatment. Hopefully won't need often.