Green Synthesis of Silver Nanoparticles by Leaf Extract of Argyreia nervosa & Anticancerous Activity

Many scientists are making their best efforts to battle against the disease known as cancer. Cancer is an abnormal mass of tissue which may be solid or fluid filled, that results when cells divide more than they should or do not die when they should. Intervention and treating the cancer can be divided into alkylating agents, antimetabolites, antimitotic, antibiotics, hormones, targeting agents, topoisomerase inhibitors. But all these have side effects like alopecia, myelo suppression, anemia, lymphomas, leukemia, etc. Plants are the new economic and higly effective resources for drugs to treat the cancer. Herbal plant of botanical name A. nervosa, belongs to family- Convolvulaceae. It is a woody climber and is also called by the name Elephant Creeper. It has wide range of pharmacological activities (aphrodisiac, immunomodulatory, hepatoprotective, anti-oxidant, anti-inflammatory, anti-hyperglycemic, anti-diarrheal, anti-microbial, antiviral, nematicidal, antiulcer, antiseizure drugs, pain relief action and CNS depressant propeties). Silver has been recognized as a nontoxic, safe inorganic antibacterial/antifungal agent used form many years. Silver shows a very high potential in a number of scientific applications, more particularly in the form of nanoparticles. As it is naturally prouduced by green synthesis it reduces pollution and is ecofriendly. Silver nanoparticles can be successfully used as antitumor agents due to their antiproliferative and apoptosis-inducing properties. These are considered potentially ideal for cancer treatments.