Coagulation Cascade || USMLE

My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[chrischen]

My silly way to remember the relationships:

PTT - play table tennis (you play table tennis inside = intrinsic). Its heparIN
PT - play tennis (you play tennis outside = extrinsic) By deduction warfarin is here.

[sarahjanesalvan]

You can remember what drug is for which pathway by thinking of the alphabet. H for heparin is followed by I for intrinsic, W for warfarin is followed by X for eXtrinsic. (Heparin=Intrinsic; Warfarin=eXtrinsic). I just came up with this after watching your video, thanks so much!

[dashcamera_daily]

Missing factors
Factor 1 = Fibrinogen
Factor 3 = thromboplastin
Factor 4 = Calcium
Factor 13 = Fibrin stabilizing factor

[mscrawford]

I always remember that PTT is affected by Heparin, because PTT has two "ts" next to each other (like tt, or TT) which resemble the capital letter "H" although it depends on your font/handwriting. This might just work for my brain only, but hopefully it helps others! :)

[witwatersrand]

warfarin will affect both extrinsic pathway and common pathway...remember Vit K dependent factors 2, 7, 9 and 10

[careplushospital]

HINT : HEPARIN INTRINSIC PATHWAY

WEPT: WARFARIN EXTRINSIC PATHWAY

HOPE THIS CAN HELP YOU REMEMBER .

[pragyadwivedi]

Write a capital I ( the one with bars on the either end of the line) and turn it 90 degrees; it becomes H.
I for intrinsic; and H for Heparin.

[raphaelmalpica]

Thank God for this video!!! If you go to page 383 of the Hematology and Oncology chapter in the First Aid for USMLE 2016 and look at the coagulation cascade! Thanks to this video it made it way much easier to deal with. Gracias!

[xoxomikimouse]

I remember warfarin with extrinsic b/c "To WAR with your EX"
WAR= warfarin EX= extrinsic

[kishahimaya]

I remember heparin=PTT and warfarin-PT by remembering to make 10 letters for both so... it goes like this

H E P A R I N ( P T T ) = 10 letters
W A R F A R I N ( P T ) = 10 letters

[marissacopasweaver]

I really like this mnemonic, but my OCD struggles with the final picture because the last step of the common pathway is Fibrinogen (I) to Fibrin (Ia). So I add "1" to the bottom of the common pathway and said that it stands for "One common math problem (pathway)".

[af]

you should really teach this stuff part time. your really good at explaining material

[toherstudies]

My professor had this mnemonic which actually helped bc I love Brad Pitt haha

(brad) PiTT -- intrinsic pathway, PTT
(I love) PeTs -- extrinsic pathway, PT

Hope that helps!

[christophertatman]

E (for extrinsic) put on it's side makes a W (for warfarin).

[spideylover]

two times five that's 10, minus 1 that's 9 quick maffs.
ya dun know.

[dr.poornaprajna]

PT (physical education teacher) is always OUTside. He is FAST and always ready for the WAR!
PT → OUT (extrinsic pathway) → FAST (fast reaction) → WAR (warfarin)

[kaitlynestes]

a great way to remember is we measure INR aka PT for warfarin -> warfarin blocks formation of VitK dep factors --> 2 7 9 and 10 --> 7 has the shortest half life and degrades first = easy way to check warfarin levels bc its the first factor to go

[MrTiwarygunda]

(warfarin)War outside-extrinsic
(Heparin )Hepatic inside body -intrinsic

[xlovelykissesx]

I like to remember that in WAR(farin) you need a PT (physical therapist)

[mayuribirajdar]

Heparin is already present in our physiological system in mast cells but inactive anticoagulant, ,,so it's present inside= Intrinsic and oppsite to it warfarin = extrensic