The Orexin Hormone | What Does Orexin Do In Sleep?

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TIMELINE:

00:00 Introduction
00:51 Are you struggling with sleep?
01:36 Orexin controls sleep/wake cycles
03:28 Orexin controls your appetite
04:21 Orexin and energy balance and dopamine
05:03 The effect of orexin on brain health
05:48 The effects of fasting on the wake-promoting neurotransmitter orexin-A
07:59 The fasted snack
09:21 Improve orexin with foods

REFERENCE:

The effects of diurnal intermittent fasting on the wake-promoting neurotransmitter orexin-A

Food restriction has been demonstrated to increase the alertness in different species and to increase the levels of the wake-promoting neurotransmitter orexin. We hypothesized that diurnal intermittent fasting (DIF) increases orexin-A levels during fasting. Therefore, we conducted this study to assess the effects of DIF, during the month of Ramadan, on orexin, while controlling for lifestyle changes that may accompany Ramadan such as sleep duration, bedtime and wake time, energy expenditure, light exposure, and food.

Your Diet Can Boost Brain Function: The Link Between Orexin Cells And Food Decoded

Role Of Diet In Keeping Orexin Cells Active

The intensity of orexin cells signals can be tuned or influenced by diet. Orexin cells are uniquely sensitive to changes in the body's levels of certain dietary macronutrients, such as sugar and some amino acids. The potent inhibitor for orexin cells is glucose. When the level of glucose rises in the body, the cells stop generating their wake-promoting signals. In contrast, dietary non-essential amino acids i.e., those that our bodies can make are potent stimulators of orexin cells. Most foods containing proteins, such as eggs or tofu, are also responsible in keeping these cells alert.

That is how; if our orexin cells are provided enough stimulants to stay awake, our brain will also be awake. Experts also say that people who do not consume enough food might suffer from conditions like narcolepsy.

#FastingLifestyle #Sleep #FastTrainingWeek
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Please note the following medical disclaimer: By viewing this video you understand that this video is for educational purposes only. It is not intended to substitute for professional medical advice and should not be relied on as health or personal advice. Always seek the guidance of your doctor with any questions you may have regarding your health or medical condition. You also understand and agree that the terms of our Privacy Policy and Terms of Service apply to your interaction with us.
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Dr Mindy, please do more videos about this, I’ve had sleep issues for many years - I am now post-menopausal.

JoAnnCarpenter
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Brilliant Dr M! Aminos it is! Yes, please do a part 2! I notice I have a little more energy so I need less sleep most times in a fasted state. But when I start eating again I sleep really good.

Artzenflowers
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I’ve had insomnia for years. I would love a part 2 with a “sample day of fasting for sleep”, how to break the fast, recipes for fat bombs, etc. Do we drink water or any other liquids during fast? I just want to see the details & timing of the 24-hour fast & how often we do it, etc. Thank you! 🙏🏻☺️

slr
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That method (Ramadan fasting) is the opposite of what I've heard others say, which say eat when the sun is out and don't eat after it goes down, which aligns with I have personally found as well. Eating after dark and near bed is the worst for me.

missygee
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My sleep was horrible during fasting week! It was excellent the week before. And I’ve been working on sleep for the last 3 years. Finally in a good place and the 17 hrs fasting brings me back to waking at 3-4 am. Cortisol spike? Glucose dump? Idk. Just know that fasting while being a cycling woman is a challenge!! I can’t wait for your book!!

arielsol
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Companion guide please! Thank you for everything you do!

stephaniesimmons
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Wow! I have never heard of the orexin hormone. I'm going to do a little bit of research. thanks!

marierose
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Thank you for sharing your wisdom and knowledge.

Yes please I would like the Companion guide

muzaknmoveezla
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Dr. Mindy thank you so much for this information and all that you do! I've never heard of the hormone orexin. Could you explain please a little more about why this type of fast turns on the 'orexin switch"? oh and Companion Guide 😊

auroraseyets
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Pls describe a day in detail including what “fat” means

mmccrownus
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I'm on OMAD person, havent eaten today and it's almost Saturday. Refrigerator is broken, but at least the meat freezes, ice cubes over time, never ice cream. I have a terrible apt mgr and have had to call every agency in the book to get things done around here. Going to sue him for a slip & fall and discrimination against a senior. But ofc the numbers I called today havent called me back and it's the weekend, sigh. Thx Dr M!

FastingStarChanelNo
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Hi Dr. Mindy! I love your content! I’ve been having trouble sleeping at night for the past two years. I’m 52 years old and just began menopause. I also work 12hr-night shifts and have been doing so for the past 26 years. I’ve never had any problems with sleep before (day or night). I still sleep relatively well during the days when I’m working but on my nights off 😳I’m wide awake. I keep trying different methods to help me on my nights off (sunshine during the day, magnesium supplements) but nothing consistently works. It’s very frustrating! I definitely need some help!

Tamzie
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More info please.. companion guide please

so appreciate you Dr Mindy. Tnx so much
I’m 82yrs young; lost 85 # fasting but have been stuck for past 9 mos. Going to try varying my fasting & doing all that u suggest. Hopeful for first
time in long time!!
Not tecky so concerned about Keto Mojo function ??
Have about 35# yet to lose. Also have sleep issues & flabby arms.
Extreme back, neck, shoulder & wrist pain( arthritis) fasting has NOT changed this in many years of following various plans. Hopefully your info will help. God bless you!
Judy

judyferrera
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I am going to have to try the added amino acids and pick one of these fasting methods. Trying to figure out narcolepsy.

KSAalto
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I have Narcolepsy Type 1. I am working with a Neurologist in regards to treatment but have always preferred a holistic healing option over medications. Is Narcolepsy and Cataplexy a disorder that can benefit from Fasting. I would love more information on the Autophagy fasting program and specifically how to engage in this so that I may see whether fasting is beneficial. Thank you.

lisaglenn
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Good afternoon I'm new to your channel I'm 41 years old and I'm 5 ' 06" in height and about 260 in weight and of lately my body is crying out i feel sick must day im away tired no energy where should i start

triciastewart
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I really like the idea of fasting for 17 hours then break it with fat bombs to go to 24 hours for a month. That sounds really do-able.

sophie
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This is fascinating.... do you take the amino acids with your meal or during the fasting hours?
Also, with Ramadan fasting do I understand that you eat during the darkness hours? 💕

kathylotter
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Thank you Dr Pelz, love your videos, May Allah bless you🌜💚🤲

acacianorison
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🥰😍🤩 Like 2 know more about Amino's PLEASE

shellsea
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