Andrew Mente - Carbohydrates and Fat Consumption and Cardiovascular Disease

Andrew Mente - Carbohydrates and Fat Consumption and Cardiovascular Disease: A More Complete Picture

From the JumpstartMD Weight of the Nation Conference 2018

[Kinkle_Z]

I thought my brain was going to melt with all that info and statistics but I stayed focused and made it through. PURE basically confirms what we already know.

[martinirving]

Full-Fat dairy was shown to be protective. Can't be emphasized enough.

[martinirving]

To summarize and reiterate: the current guidelines to keep saturated fat below 10% is not supported by their data (or any data, for that matter).
The WHO is the really big offender in promoting the vegetarian agenda and facilitating that poor people are kept in poor health and die sooner.

[blackbirdsinging]

Epidaemiological studies can never demonstrate causation and contain many confounders that are difficult to make reasonable adjustments for.There are far better studies, for example the Minnesota study, The Womens Health Initiative.The cholesterol hypothesis has been debunked thousands of times in well executed research for well over a decade.Not one well conducted study has ever demonstrated a causal link between higher cholesterol and higher all cause mortality.Even studies on familial hypercholesterolaaemia groups could not establish a statistically significant increased incidence of CVD mortality and only a 0.01% increase in all cause mortality.Inversly low cholesterol levels were seen to cause earlier deaths from all causes.All carbohydrates lead to significant increases in insulin, even the so called ' good ' ones.

[liutasx]

Correlation don't imply causation. Problem isn't that people eat carbohydrates, but overeat calories.
Any diet which enable people to lose and maintain weight (if they are overeat) is best diet for them. So low carbohydrate diet isn't any special when compared to other diets.

[ProfFeinman]

PURE is not any better than the stuff that doesn’t confirm what we know. You take a “diet” which contains a hundred variables. You get a group of people and categorize by a few of them and you correlate with outcome and you get a comparison which — here’s the catch — compares the risk of getting sick from high intake vs. low intake. In other words, the HR is not sick compared to better. It is sick on one diet compared to the other. Consider an HR of 1.5. What that means is 60:40 odds of getting sick on one or the other. And remember, “validated” food questionnaire does not mean validated as true. It means validated to have a certain accuracy which, if your luck is 70 %. All of this is meaningless. I give Dr. Mente credit for trying to get something useful out of this but it is hopeless. No physical scientist would consider this as mature science. This is juggling numbers without any understanding of error and effect size — experimental, not statistical effect size. Hu-Willett theorem: for any collection of nutrients and any disease, there exists at least on finite set of confounders such that the nutrients can be shown to cause the disease.

[NathanYoungman]

27:33 "There are good carbs and there are bad carbs... higher fruit, vegetable, and legume consumption is associated with a lower risk of total mortality."
37:22 "High diet score... 8 servings of fruits & vegetables, 2.5 servings nuts & legumes, 3 servings dairy, 1.4 servings red meat..."
39:44 "Our concluding message... eat more fruit, vegetables, nuts, legumes, dairy, meats... eat less refined grains and sugar, and sweetened drinks."

Well presented. The takeaway is not to increase saturated fat intake, but rather to eat less processed junk. Vegetarians may be eating more sugar and unhealthful processed food than those focused on eating "real food." That said, what PURE doesn't show is a reversal of heart disease like the angiograms from Caldwell Esselstyn, based on a whole food plant based diet that not only restricts processed food, but also removes vegetable oils, nuts, and animal foods (leaving only fruits, vegetables, legumes, and grains). Maybe it's also possible with a diet like Andrew Mente suggests, but so far the evidence isn't nearly as compelling.

[TBM]

The pure study is so confounded its pointless - as is the Norweigian Hunt 2 Study. You can see the funding source and bias in the first paragraph!