A full explanation about the Telomerase and the end replication problem

This video explains ehats is the telomeres, the telomerase activity, and the end replication problem

[djalitanaful]

Jesus, finally someone explained this properly. this is the 10th clip I watched and now can understand this end replication problem. thank you for sharing.

[aparnakanjhlia]

There's quite a few things missing in this video. Especially, since we're talking about the end replication problem, there is a need to mention that the lagging strand and its template strand never really fully get replicated, there's always a part of the extended DNA that doesn't get replicated. The telomere essentially has both double stranded and single stranded regions, the single stranded region of the telomere loops around and forms a knot in the telomeric region which stabilizes the ends of DNA.

[sahanapaulganesan]

Only video in the whole YouTube to explain the concept properly

[ali_karem]

Like other students, I finally found it explained correctly and logically after a lot of unuseful videos. The most convincing explanation of telomeres. Thanks alot.

[zakiyashahnaz]

The best explanation so far... I would not have understood it without this video... God bless the teacher

[katharinamazzotti]

This topic of genetics is so interesting. I hope I'll have the chance to study and research it once I've graduated. :D

[rayenaouni-od]

I have watched many videos before, but yours is exceptional and well-detailed. You helped me understand in 13 minutes what I had been struggling with for 1 hour ❤️❤️❤️👍🏻👍🏻👍🏻. Thanks a lot.

[Abhinav-kfwd]

Thank u so much. This is the best video on YouTube explaining the end replication problem and its solution by telomerase enzyme. Really very helpful video for students. God bless u !!

[mamunrashid]

Thank you for the nice explanation. I am wondering why only lagging strands are facing telomere shortenings, why not the leading strands as they also had primer at their starting points and there is no way to replace it with DNA? Could you please explain?

[benbarris]

I must have watched and read dozens of videos and articles on this topic...I finally get it now! thank you for this video.

[naderibrahim]

The best explanation i heve found on this specific topic. Great. Very simple explanation, it's like you are watching what my mind needs❤

[leoniew]

Oh my god thank you so much, I watched literally every video about this topic and then finally found a good and detailed explanation!! Finally 🤯

[Maryam_]

Your way of explaining complicated topics in such an easy way is awesome.

[dr.m.umairmajeed]

Best explaination of telomeres and telomerase

[superEriccui]

Ok so I want to clarify something. The last primer on the lagging strand is removed because it is RNA and under physiological conditions is extremely unstable. RNase will remove it THAT"s WHY IT IS REMOVED.

[poincareconjecture]

VERY CLEVER; WELL DONE, THE PROBLEM IS WHEN THE PRIMERS ARE REMOVED THE END LAGGING STRAND IS NOT "COVERED DOWN"...now i got it; good job ma'am:)

[ayeshanoor]

The best explanation I have ever found related to this topic, , I mean she made it more interesting.

[akro]

Finally someone can explain it good job👏

[josephmugagga]

i swear to God, am blown away... this is so amazing!!!

[FlamesofInferno]

Clearly narrated a beautiful story. Well explained. A layman like me can understand well. Thank you.