What is the First-Pass Metabolism? | Basic and Clinical Pharmacology

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☛📄 DESCRIPTION
Let us learn about first-pass metabolism today. In this Pharmacology video, we have provided a daily life example to understand this phenomenon more easily.

The amount of drug you take by mouth and the one that reaches the circulation are not the same and even the amount of drug absorbed from the GIT and the one reaching circulation is different.

Well, this is because the drug may undergo biotransformation reaction and get metabolized before entering the systemic circulation. This process is called first pass metabolism, also known as first-pass effect or Presystemic metabolism.

☛🕘 TIMESTAMPS
00:00 - Introduction
00:57 - First-Pass Metabolism
02:06 - First-Pass Effect
02:55 - Route of Administration
04:17 - Pharmacology mnemonic

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Love your video! I learn best with stories and this video stuck in my mind. Thank you.

wogwog