GLP-1 Agonists: Wonder Drugs of the 21st Century?

The first drug in a class known as GLP-1 agonists was approved in 2005 to treat diabetes. GLP-1 drugs subsequently proved their mettle to treat obesity and prevent major cardiovascular events and will likely soon be available to treat sleep apnea as well. Looking ahead, their action on the brain is prompting research to gauge their value in curbing drug, alcohol, and nicotine cravings. But these seeming miracle drugs are costly, not always covered by insurance, and generally need to be taken forever. How do they work, what else might they do, and how do we ensure they are accessible to those who need them most?

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[lyndeeluu]

The best medication that I have ever taken.

[sparkymark]

They're only expensive because the US charge an absolute fortune for their medications. They cost about 1/4 of the price in the UK.

[cloakster]

35:58 Great discussion… but the next major GLP-1 drug to come out will actually be CagriSema (GLP-1/amylin dual-agonist), not Retatrutide.

Would hope for that one by end of 2025, with Retatrutide following about a year later.

[GoutamDAS-lswb]

If obesity involves the brain then it would have been a good idea to include a psychiatrist on board. GLP-1 analogs helped me get over compulsive snacking which in turn helped me keep my body weight in check.

[michaelclanton]

To Elimanate heart muscle mass loss I would think an echo cardiogram could be done on 1yr use patience.

[robincallawaywelch]

The question she asked at 9:52 wasn't answered. The 2 genius doctors didn't listen.