Session 1: Bioinformatics for Infectious Diseases - Summer 2022

This program is dedicated to the study of viral diversity and its role in epidemic infectious diseases that keep re-emerging, including zoonotic spillover, transmission between humans, and the process of viral and bacterial disease development. Participants will get a chance to learn about bioinformatics and analyze genomic data by applying various analysis approaches to study viral genomes. As a result, you will learn to understand relationships between viral strains and haplotypes, find differences in sequence data, and see the implications for drug and vaccine design. This program will provide opportunities to practice analyzing data to gain hands-on experience with curated datasets from public domain collections, guided by experts with bioinformatics experience and knowledge about virology.

Today we’ll discuss about the Scale of Sequencing information available in GenBank - Metagenomic Viral Sequencing - Data Formats for Sequencing Data - Overview of NGS: Reads & Sequences - Alignment, annotation and non-mapped reads - Alignment to databases of viral genomes - Exploring NCBI SRA - Practical Hands-on analysis on T-Bioinfo Server: Visualization on J-Browse - Understanding an example project: Spodoptera frugiperda