Meat-based vs Plant-based Diet for Longevity | David Sinclair and Lex Fridman

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GUEST BIO:
David Sinclair is a geneticist at Harvard and author of Lifespan.

PODCAST INFO:

SOCIAL:

[jameslay]

What I love about Lex is he encourages points of view that might be contrary to his own. It inspires me to do the same in my own life.

[driedmango]

This was great. The only thing I’m skeptical on is what he says about fruit. Every time fruit is brought up he talks about avoiding “fruit juice” and “adding sugar” or “cheesecake”. This is not the same thing as the blueberries I add to my oatmeal or smoothies

[Singood.m]

1:46

"If I try to overeat on steak, which I actually did, I had a Chicken. A Fried Chicken, specifically. I felt terrible...
So now I'm at the point where If I want to binge on meat and fried foods I just can't.. "

He confuses a red meat Steak with a Fried meat chicken, and conflates meats with fried foods, implying all meats are fried. Is this a lexical mistake or obvious bias leaking through? It's no wonder he's with Harvard, an institution that has done it's absolute darndest to smother and gatekeep nutritional information.

[fulmarmusic]

Fruit is amazing for you, however, it has to come with the fibre, so it slowly releases into your body. If you down sugars too fast, your blood-sugar levels spike big time.

[hynjus]

Regarding the fasting studies on mice, one thing that isn't mentioned ever is that mice have waaaay faster metabolisms than humans. So once a day for a mouse is a much more intense fasting regime than once a day for humans. I'm not sure it's possible to figure out what the human equivalent period is.

[Boomboxin]

I feel like Lex is getting better conversationally, he leaves more and better points for his partner to use as a springboard to their point

[Euterp]

Make sure you consult a physician and/or make incremental changes to your diet. I went all in on spinach 3 years ago and found out this is the worst food you can eat (in more than very small amounts) if you are the 10-15% of the population inclined to kidney stones (which I hadn't had before). Also, a kidney stone is not just incredibly painful, it can damage your kidney. Hoping this comment can help just 1 person avoid this problem

[WikiPeoples]

What he said about WHEN you eat really resonated with me. I can eat ANYTHING in the morning and feel good, no crash, nothing. Giant burrito packed with rice in the morning? Totally fine. That SAME meal in the afternoon, or evening, will put me into a coma. My guess this has to do with the natural spike in cortisol in the morning, and this somehow either counteracts the tiredness effect of carbs, or, even works synergistically with a bolus of carbs. Sans cortisol, carbs spike insulin and make you tired as fuck.

[kamarifit]

Finally a recognized figure in medicine and in the mainstream who is able to speak the truth when it comes to the science and not just cater to what the general public desires to hear. Which is good news about their bad habits.

[Mafyu]

The problem with diet advice is that apart from the common advice of avoiding sweets and alcohol there is a lot of confliction. For instance: carbs or no carbs? fruit or no fruit? caffeine or no caffeine? lots of veg or lots of meat? Also eating one meal a day seems to be getting recommended a lot but then it seems problematic to squeeze the day's calories into one meal whilst keeping it healthy.

[paulmcintosh]

We need to get Lex to moderate a nutrition debate - plant vs animal - between David Sinclair and Paul Saladino! Who’s on board for this?

[angelgutierrez]

What an amazing video, I’m very grateful that the internet opened the possibility of learning from great minds on how to improve our daily lives.

[rexyz]

Lex sounds like he is sitting in a campfire telling scary stories

[OnwardsAndUpwards]

There is a lot of defensive people in the comments here. Food culture is as strong as religious indoctrination. People don't want to think what they do is wrong. Instead of assuming we know the answer we should be asking questions.

[Jamie.Richards]

I'm glad to see him on the podcast. It concerned me how often the meat only and keto diets are discussed without someone, like David Sinclair, to challenge it.

[dasbof]

1:25 "occasional dessert" much should be said about "cheating" on your diet and the triggers it has for most people. This causes many people to fall of the wagon and ending their diets. I like Dr. Robert Cywes idea of sugar/carbs being addictive. I think you need to break that addiction by going low/no carb for quite some time to reset you body AND your mind. Sugar is like cocaine.

[lovetolearn]

Eating in an 8 to 10 hour window is what allowed me to loose the last ten lbs and flatten my stomach. To be honest doing the 16 or so hour daily fast is the only think that keeps my stomach flat

[richspizzaparty]

Fasting. There’s a reason cultures have embraced it for generations.

[CastIronSteak]

The only rats that lived longer were the ones that ate once a day, regardless of all other factors. That alone tells us so much.

[accord]

The key is in the gut microbiome. That really needs to be studied and tested alot more.