A Clinical Discussion of Mixed States in Bipolar Disorder

Mixed states in Bipolar Depression entail simultaneous occurrence of both manic and depressive symptoms.1 In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the previous definition of a “mixed” bipolar episode (which required presence of concurrent manic and depressive symptoms) was replaced with a “mixed features” designation that captures subsyndromal symptoms and can be applied to episodes of depression, hypomania, or mania. Dr. Ketter discusses the clinical implications, including how these new definitions could impact diagnosis and treatment.

Featuring:
• Terence A. Ketter, MD
Professor Emeritus at Stanford University; Founder and Chief of the Stanford University Bipolar Disorders Clinic

#MentalHealthMatters #Depression #BipolarDepression #MajorDepressiveDisorder #MDD #MentalHealth #Psychiatry #Bipolar

1Diagnostic and Statistical Manual of Mental Disorders. 5th ed. 2013. 2. Fagiolini et al. CNS Drugs. 2015;29:725-740.

Terence A. Ketter is a paid consultant to Otsuka Pharmaceutical Development & Commercialization, Inc.

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