The Sweet Side of CAR-T Cells | Avery Posey, Jr.

Avery D. Posey, Jr., PhD, is an assistant professor in the Department of Systems Pharmacology and Translational Therapeutics, a member of the Parker Institute for Cancer Immunotherapy, and a research health scientist at the Philadelphia Veterans Administration Medical Center. Posey holds a PhD in genetics from the University of Chicago, a BS in biochemistry from the University of Maryland, Baltimore County (UMBC), and a second BS in bioinformatics from UMBC. Posey completed postdoctoral training in the laboratory of Carl June, where he generated glycosylation-specific chimeric antigen receptors to precisely target tumor-glycoforms of MUC1. The Posey Lab focuses on the development of novel cancer therapies that genetically alter cancer patients’ own T cells to improve the ability of the immune system to fight cancer. This research involves antigen discovery to identify tumor-specific targets, engineering strategies to surmount the tumor microenvironment, and altering the signaling influences of T cells to develop robust anti-tumor efficacy.

Stacie Dodgson, PhD, Scientific Project Manager for the Gladstone-UCSF Institute of Genomic Immunology moderates the Q&A.

This talk was presented during the Gladstone-UCSF Institute of Genomic Immunology Symposium in 2021. The Gladstone-UCSF Institute of Genomic Immunology is creating an ecosystem that brings together experts to develop transformative opportunities to harness the immune system to treat patients across a broad range of diseases.