Cytotoxic T cells

Animation by Etsuko Uno, Walter and Eliza Hall Institute

The animation illustrates how cytotoxic T cells kill virus-infected cells. The movie shows how the body, in response to a virus infection, can produce clones of cytotoxic T cells that specifically target and destroy infected cells. The movie highlights key molecules that enable the cytotoxic T cell to kill only infected cells while leaving healthy cells unharmed.

[Nawmps]

Mad respect to the camera crew that shrunk themselves down and risked their lives for education

[Tiniuc]

These sound effects make me feel like I'm watching Doctor Who. I love it.

[YouGotsTheRabies]

The immune system seems to be hell-bent on revenge.

[itcamefromthedeep]

Infected Cell: [grabs T-cell] "Rico! You know what to do!"
T-cell: "Yes sir!" [cocks cytotoxic granules]

[yimingqu]

the chewing sound makes the infected cell sounds delicious....

[etherflows]

WEHI animation is WOW! We need full length documentaries of this!

[alexandrabrighton]

OMG!!! What a perfect explanation!!!
I absolutely love this way of learning. Thank you very much for the content ❤️

[NotoriousPyro]

Can barely hear the narrator over the sound effects.

[williamwixon]

Thank you so much everyone at WEHI for producing and presenting these astounding animated videos! Absolutely jaw-dropping! I wish everyone could/would watch these videos! I’m sorry but they seem to have what I would assume is the opposite effect of what they are intended is that I watch these videos and I can’t possibly imagine that something that complex could be created by accident/evolution, and how in the world did it function in a lower revolutionary state a less complicated state I can’t imagine that it could function at all unless it’s fully formed and perfect as it is, everything relies on such absolute precision.

[xoRial]

This raises some questions:

1. why virus-infected cell expose the virus fragment? if they can recognize virus on their own, they could just turn on apoptosis and not waste time/energy of the body immune system.

2. how does activated t-cell knows not to attack the 'scouting' cell, if the attack and activation are triggered by same molecular complex?

[Microbex]

I dont pay enough homages to my body. Thanks t cell and yall.

[Keliciabrat]

T-cells : you had one job aunti gen.

Aunti gen: 0_0

[MinskyDoxsky]

is the mic inside someone's mouth while chewing?...

[GhazalAzadi-fq]

amazingly informative! enjoyed the sound of binding T-cell receptor and virus peptide MHC!

[DaeZey]

Do infected cells display virus bits because cells are always displaying just a little of what they're making inside? In case is virus and needs touch of death?

Also, are cytotoxic and killer t-cells the same?

[NotAvy]

Helper T Cells :
WTF! I am in the charge of activating T cells ....and YOU DELETED MY ENTIRE ROLE!!

[doctorvimalkatarmal]

bro.. respect for u.

u done fabulous animation... perfect

[sbarr]

I like the chewing / slurping sounds at 5:15.

[花だ吸い散ろ]

Did he voice the medieval total warfare? Lol

[opufy]

whoever is in charge of the body deserves manager of the year