Misoprostol Mnemonic for Medicine & USMLE

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Misoprostol is a prostaglandin E1 or PGE1 analogue. Acting on the stomach, misoprostol reduces the secretion of gastric acid, and also increases the secretion of mucus forming the protective lining of the stomach wall. These two actions make it helpful in the prevention and treatment of peptic ulcers, specifically ulcers induced by NSAID use. Next, the action of PGE1 on the cervix and uterus can lead to uterine contractions, which can be used to induce labor or cause abortion. Non-specific adverse effects of misoprostol use include diarrhea and abdominal pain.

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