Pre-clinical AAV production and optimization: Not as easy as it looks! | GenScript

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This webcast will discuss:

Introduction to AAV in gene therapy.
Some recent advances in viral vector production.
Current challenges and solutions of pre-clinical AAV production.

Adeno-associated virus (AAV) is the most popular vector of choice for gene therapy because of its low immunogenicity and ability to infect numerous cells and tissue types. However, with hundreds of gene therapy trials ongoing, manufacturing large quantities of viral vectors is becoming an increasing challenge.

Services GenScript offers related to the topics discussed:
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That is awesome ❤. Great great job. Currently I work with polycistronic genes that are very much in the limit of the cargo that AAV accepts, 4.8-5 kbp, making it very challenging, it would be great that Genscript develop strategies for this kind of cargo, larger than 4.5 kbp without the need to resort to infect with complementary plasmids to work in trans

ericamadobegines