Protein Structure and Folding

After a polypeptide is produced in protein synthesis, it's not necessarily a functional protein yet! Explore protein folding that occurs within levels of protein structure with the Amoeba Sisters! Primary, secondary, tertiary, and quaternary protein structure levels are briefly discussed. Video also mentions chaperonins (chaperone proteins) and how proteins can be denatured.

Table of Contents:
00:00 Intro
0:41 Reminder of Protein Roles
1:06 Modifications of Proteins
1:25 Importance of Shape for Proteins
1:56 Levels of Protein Structure
2:06 Primary Structure
3:10 Secondary Structure
3:45 Tertiary Structure
4:58 Quaternary Structure [not in all proteins]
6:01 Proteins often have help in folding [introduces chaperonins]
6:40 Denaturing Proteins

*Further Reading Suggestions*

Related to Protein Misfoldings:

Learn About "The Protein Folding Problem":

Factual References:

Reece, J. B., & Campbell, N. A. (2011). Campbell biology. Boston: Benjamin Cummings / Pearson.

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MUSIC:
Our intro music designed and performed by Jeremiah Cheshire.

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TRANSLATIONS:
Hindi Subtitles Credit: Alisha Aggarwal

[thisislydiarae]

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Everything about this video is super helpful! The animations, the explanations, and even the voice, as weird as that sounds, but the narrator sounds so enthusiastic that it helps to pay attention and actually retain the information, rather than a monotone robotic bio teacher. THANK YOU!!!

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[linusbao]

oh mah gawd those chaperonins are the cutest lil things i have ever seen ever

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[nurshahira]

Just in time! My lecturer is currently covering Protein Structures and I was soooo lost :')