Drug Tolerance and Dependence | General Pharmacology | Drug Tolerance | Drug Dependence

Tolerance happens when a person no longer responds to a drug in the way they did at first. So it takes a higher dose of the drug to achieve the same effect as when the person first used it. This is why people with substance use disorders use more and more of a drug to get the “high” they seek.

Tolerance is what happens before dependence is formed. The body starts to recognize a chemical because it has been administered too often. When the body recognizes the chemical, the effects aren’t the same and more of the drug is required to achieve the desired effects. Those with a chemical tolerance will take more of a drug or drink more alcohol to feel the way they want to. Examples of this will be a drug user taking twice the dose or an alcoholic drinking hard liquor when everyone else is drinking a glass of wine.

Dependence means that when a person stops using a drug, their body goes through “withdrawal”: a group of physical and mental symptoms that can range from mild (if the drug is caffeine) to life-threatening (such as alcohol or opioids, including heroin and prescription pain relievers). Many people who take prescription medicine every day over a long period of time can become dependent; when they go off the drug, they need to do it gradually, to avoid withdrawal discomfort. But people who are dependent on a drug or medicine aren’t necessarily addicted.

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[indrajith]

Thank you so much sir not only this video for everything you post so that students can understand easily and thank you for making it free . Good peoples heart do it

[debwiser]

Here I Comes For Clearing doubt About "Cross Tolerance"....
And I am really satisfied with that

[avadheshbauddhrana]

Thank you soo much sir ...aapne bahot hi saral language me samjhaya ...bahot hi benifite sabit hua mere liy ...thank you so much once again 🙏🙏🙏

[priyayadav]

Thanku sir.. u make so easy .. now pharma is my fav sub in 2 year

[aparajita]

Please upload a video on drug used in clinical toxicity, poison and their treatments, and barbiturate poisoning, heavy metal and insecticide and organophosphorus poisoning.

[totonmusicaltrip]

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[saurabh_sahani]

बहुत simple और behatar h sir.
Nice 👍.
Plz upload adverse durg reaction..
K. D. Triphati से..

[Imranmansuri]

Bahut ache se samjhaya sir Apne Esi hee video or banate rahiye please

[HARDMAN.]

Please its request keep all your video title accordingly unit wise to sallabus and mention unit 1, 2, 3 etc. afterwards. Its so hectic to find your videos in youtube. Thankyou.

[Fact-talks-qo]

Sir please make in more detail on drug dependence coz In PSM (3rd MBBS) it covers a huge portion in Mental Health chapter 🙏

[VivekSingh-xnlx]

Explanation method or tech. To teach your awesome sir .... With example very nice sir thanks for it

[drnaturopathy]

Pls make such white board lectures fr MBBS.awesome vdos

[Satendrakumar-qghu]

Thank you so much sir but sir
Ye pata nahi chalta ki kon sa video kiska part h
So sir please lecture number dal diya kigiye
Thanks sir

[mrmostofaahmed]

Thank you so much sir 💖💖💖💖
Love from Assam.. sir ❤️❤️❤️❤️

[snow]

very informative video . Thank you Sir :)

[FarhanKhan-riwh]

Sir Rabbit tolerate atropin kya ye human m bhi tolerance couse kregi

[rehenajsarkar]

Drug tolerance and dependents details discussed in Sir plz upload this topic ....

[gratyfix]

Issi principle ko apply Kertei howei
Bht sei medival kings nei poison sei resistance develop Ki thi
Am I right
This is pharmacology applied in history

[medicalscience]

I liked video even before watching, very well 👍🏻

[rehenajsarkar]

Sir please uplode another video of this topic in Plz sir