Understanding Parkinson's disease

Parkinson's disease is a neurological condition that affects the brain and other parts of the nervous system. The gradual loss of nerve cells leads to a suite of characteristic motor and non-motor symptoms. What causes these cells to die and how the pathology develops in the nervous system are not yet clear but multiple lines of investigation are being pursued to answer these questions. In this animation, we explore some of the latest in Parkinson's disease research.


Correction 16 Dec 2019 : This video has been re-uploaded due to an error in the previously published version. The previous upload did not contain the correct logos in the opening and closing sequences. We apologise for any confusion caused.

[NatureVideoChannel]

Correction 16 Dec 2019 : This video has been re-uploaded due to an error in the previously published version. The previous upload did not contain the correct logos in the opening and closing sequences. We apologise for any confusion caused.

[nikoxxx]

my father past away a week ago. he diagnosed with pd since he was 40. the most heartbreaking thing i saw in life is to see him deteriorating so badly that he couldn't walk without falling every few minutes and could not talk properly until no one could understand him And he could not control his jaw and would drool endlessly.even though he became a shell of his former self he never complained. he fought through everything. He fought to live another day.he was so strong but the combination of pd and covid 19 that he got in nursing home was too much.. he even overcame covid after 2 weeks which he was sedated and ventilated.He recovered but got pneumonia and a hole in his lung.and he couldn't fight anymore.he was a true hero.i'm so sad. he suffered so much.he didn't saw anything good in his life just fought to survive.r.i.p. father. i will carry on your legacy to hold on to life and fight everything and never surrender

[xtnzxxf]

Muhammad Ali: Do you know what its like.. to have your body betray you?!

[jdanderson]

My father has PD dementia. He is 85. Has slowly been going down hill for years (especially the past 10 years). The falls. The ER visits. Still Dad fought through it all. Still lived on his own
and still relatively independent. Seven weeks ago he got covid. He was absolutely destroyed...wiped out. He recovered. However, as in any health care episode encountered (especially the
past 4-5 years) he rebounds...BUT never to the level he was at before the event. Today, it's like he fell off a cliff both mentally and physically. A STEEP decline from which there is no
recovery. 24/7 skilled nursing/hospice care. Now hospital bed and wheelchair bound. We are combining hospice & palliative care. Keep him as comfortable as possible while dies.
We all die but this is nor way to go out. PD is one of the more horrific ways to "shuffle off this mortal coil"! pray he doesnt last more than a few months.

[black]

Thank you for making this video, I’ve been watching videos about how Parkinson’s works for over an hour and this one blew the other’s away by leaps and bounds. This may be the best video about Parkinson’s on YouTube, it’s the best I’ve seen, by far.

[promisegreg]

I quickly came here to find out the naming of this disease when I saw how Mohamed Ali died😪😪

[itslinytofficial]

My mom's dad has it... god bless him 😭😭🙏🙏 It is sad to see him shake and staying in the same position everyday and needing someone to help him

[Anthrostatic]

that background music is a proof that good conscience can keep Science peacefully :)

[tanveersingh]

Wow what a great video love the presntation and the visuals.

[serbian_knife_fight]

My grandma was diagnosed with this a few years ago, and I only learned it was worsening now. I worry a lot for her, and I can’t see her since she is across the country and the pandemic. I’m learning some music she loves on my saxophone, and I hope it will cheer her up and help with her recovery or at least bring her solace because she may be developing dementia

[abhishekshah]

This is gold. Thank you for making these videos.

[ygycixm]

Thank you very much. This video is also very useful for Indonesians, Filipinos, and Vietnamese who are aiming for the national examination. Parkinson's disease is often asked in the exam, so if I understand the points, I can score.

[eaglemotive]

People on Calcium Channel Blockers tend to get Parkinson's and Psoriasis. There is calcium buildup in the brain, because the neurons that use calcium to signal the release of neurotrnansmitters such as dopamine cannot accept the calcium in the calcium ion channels. The neurons are not firing as they should.
This happens in the skin too, because in each step of differentiation of skin layers, calcium ion channels must be functioning for the process to happen. The skin begins to malform and becomes incomplete. The epidermal layer is very weak and you get inflamed infected broken skin, and you can see the white calcium deposits in the patches of malformed skin.
The solution to these diseases is to stop taking calcium channel blockers. To get rid of the built up calcium deposits, take Calcium Disodium EDTA. Sublingual intake is the most effective method second to IV Chelation treatments.
Next to open your Calcium Ion Channels take Vitamin K2 MK4. It opens Calcium Ion Channels. It is what is needed at the cellular level to do this. MK7 stays in the blood longer, yes but it does that because your cells can't use it until it gets converted to MK4.
Whether you are on Calcium Channel blockers or not, if you have Psoriasis or Parkinson's these steps may help resolve your condition.
Get rid of the Calcium Deposits and open the Calcium Ion Channels.

[allenshaw]

Oh boy, this is the best video on Parkinson's for the lay audience I've ever seen!

[bellacristhyarenales]

Hi, I'm from Peru and I'm a university student who helps his grandfather and give him love in the last days of his life. My grandfather of 78 years has Parkinson, but also he only have one leg since 24 years ago . And his stump hurts a lot. And it makes me very sad to hear how he complains about his pain at night (he can't sleep well), the pain comes about 6 to 7 times a day and then it goes away. Sometimes I feel useless because I don't know what to do when he suffers that pain. But I think that Parkinson's also affects him in something... I only tell you in all honesty.

[rennovilela]

I am astonished, this animation is beautiful

[RalfStephan]

What is not mentioned, there is also the infection hypothesis, just like in Alzheimer's, with a recent paper finding fungal proteins in Parkinson brains.

[Thatsaspicymeatball]

There's got to be a way. Given enough research, enough money and enough time, surely it's curable.

[AMAZINGSTUFFY-lpjg]

Just buy an Aquacure ac50 or an Osmio infinity machine? JOB DONE!!!

[RohitPant]

Function of Alpha-synuclein: The main function of α-synuclein would appear to be the control of neurotransmitter release, through effects on the SNARE complex. Recent evidence, to be discussed below, suggests that this physiological function may provide insight into the aberrant function unleashed in disease states.