filmov
tv
How Maternal Gut Bacteria Influence the Development of baby and Autism-Linked Immune Problems??
Показать описание
How Maternal Gut Bacteria Influence the Development of baby and Autism-Linked Immune Problems??
Autism-Linked Immune Problems Are Caused by Maternal Gut Bacteria
Children diagnosed with autism spectrum disorders (ASD) often also suffer from inflammation of the gut resulting in gastrointestinal (GI) issues.
A new study based on mouse models of autism, led by scientists at Harvard Medical School and the Massachusetts Institute of Technology, uncovers underlying mechanisms that trigger ASD-linked gut inflammation and GI symptoms.
The researchers show exposure to maternal inflammation in the womb increases susceptibility to bacteria-induced gut inflammation in the offspring later in life.
The study zeroes in on interleukin-17A—a cytokine that is heightened in the mother following an infection during pregnancy.
The authors show IL-17A not only alters brain development in the fetus, but it also changes the mother’s gut microbiome that in turn affects the offspring’s immune system by altering the chromatin landscape in a subset of immune cells called CD4 positive T cells.
This change in immune development primes the offspring for inflammatory attacks of the gut after birth.
......
The Original News link:
...
If you have any issue regarding this news content then kindly message at:
Autism-Linked Immune Problems Are Caused by Maternal Gut Bacteria
Children diagnosed with autism spectrum disorders (ASD) often also suffer from inflammation of the gut resulting in gastrointestinal (GI) issues.
A new study based on mouse models of autism, led by scientists at Harvard Medical School and the Massachusetts Institute of Technology, uncovers underlying mechanisms that trigger ASD-linked gut inflammation and GI symptoms.
The researchers show exposure to maternal inflammation in the womb increases susceptibility to bacteria-induced gut inflammation in the offspring later in life.
The study zeroes in on interleukin-17A—a cytokine that is heightened in the mother following an infection during pregnancy.
The authors show IL-17A not only alters brain development in the fetus, but it also changes the mother’s gut microbiome that in turn affects the offspring’s immune system by altering the chromatin landscape in a subset of immune cells called CD4 positive T cells.
This change in immune development primes the offspring for inflammatory attacks of the gut after birth.
......
The Original News link:
...
If you have any issue regarding this news content then kindly message at:
0:03:26
0:06:34
0:01:50
0:02:13
0:12:24
0:05:31
0:29:20
0:01:48
0:10:04
0:02:52
0:05:25
0:30:55
0:49:12
0:13:04
0:03:27
0:02:58
0:16:32
1:26:03
0:00:42
0:19:11
0:24:10
1:22:28
0:07:36
0:57:05