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Adenosine Mnemonic for USMLE

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Adenosine is an extremely short-acting antiarrhythmic drug that slows cardiac nodal tissue. It accomplishes this mainly via an increase in potassium efflux and a decrease in calcium influx. There is a third mechanism in which vasodilation of coronary arteries also occurs. Clinically, adenosine’s effects last 10-15 seconds, making the drug useful for treating tachycardias called PSVTs, or paroxysmal supraventricular tachycardia. Slowing down of conduction at the AV node can disrupt the timing of reentrant circuits, restoring patients to normal heart (sinus) rhythms. Importantly, adenosine can cause brief adverse effects such as a sense of impending doom, chest pain, and flushing.
#usmle #step1 #pharm #adenosine
Adenosine is an extremely short-acting antiarrhythmic drug that slows cardiac nodal tissue. It accomplishes this mainly via an increase in potassium efflux and a decrease in calcium influx. There is a third mechanism in which vasodilation of coronary arteries also occurs. Clinically, adenosine’s effects last 10-15 seconds, making the drug useful for treating tachycardias called PSVTs, or paroxysmal supraventricular tachycardia. Slowing down of conduction at the AV node can disrupt the timing of reentrant circuits, restoring patients to normal heart (sinus) rhythms. Importantly, adenosine can cause brief adverse effects such as a sense of impending doom, chest pain, and flushing.
#usmle #step1 #pharm #adenosine
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