Scientists Just Created a Potential Cure For Diabetes - Breakthrough Explained

Relevant Nature papers here:

#breakthrough #medicine #science

0:00 The Insulin Breakthrough
1:02 The Brief History of Early Medicine
3:35 Ad Read
4:32 Medicines, Just not the Right Type
5:04 Medicine 3.0
8:23 The Dawn of Medicine 4.0
14:06 The Breakthrough Results
17:38 What's Next?

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[DixonCyderBusch]

My girlfriend was a type 1 diabetic. She also had kidney and heart disease. She looked healthy 5' 5" 120lbs. Less than a year into dating her she had a stroke. She told me she wouldn't live past 50 years old. She died when she was 37. Her name was Heather and she had two daughters.

[HebaruSan]

It's been almost two decades since a doctor explained insulin to me, and it still baffles me that my cells need a signal to remind them to not die but instead eat the ample food in the environment around them.

[Boredom_Incarnate]

As a type 1 diabetic since I was 5, I do appreciate the rare reminders that people are actually working to cure this disease. On the other hand I really wish we'd stop preemptively and wrongly labeling everything a cure. It gets very disheartening.

[G]

So... it is not a "cure" for Diabetes but rather a new and improved form of artificial insulin.

[ADDY]

The title is misleading. They haven't created a cure for diabetes, but a new form of insulin. A cure for diabetes would be a proper functioning pancreas. But great research indeed.

[PolyRocketMatt]

As a bioinformatician and someone who has Diabetes Type 1, I must say that if Novo Nordisk is able to push this through clinical trials successfully (which... realistically speaking is another 10 years or so) this can indeed really help people with diabetes. There is a huge catch however, while yes this feed is undeniably amazing, it does not cure the disease. Yes, administering insulin won't become as much of an accuracy art, but we'd still need to inject the new compound while monitoring glucose levels (as a really simple example; exercise for example can still cause hypoglycemia). This is by no means a dig at the amazing achievement, but it is still a very long ways away from actually curing diabetes.

[TechCarnivore]

It's not a cure until it's available.

[americanpancakelive]

Super amazing and interesting. Next I hope we create a cure for "clickbait" titles on YouTube.

[jeslinmx]

"Have they robbed diabetes of its terrors" feels like modern clickbait but simultaneously is such a badass and poetic way of describing it.

[RadiaCode]

In the name of science and wonderful content that makes the world better and more interesting. Thank you!

[STrm-xnpj]

I’ve been living with type 1 diabetes for 27 years now! It’s true—you often feel lonely, and I’ve taught myself not to "make a fuss." But the truth is, it’s incredibly tough to live with this condition. It becomes even harder because other people will never truly understand what you’re going through. It has definitely made me stronger, but I’m also starting to notice the neurological effects. Even so, this disease will not defeat me. I wish the same determination and energy to others who are fighting for understanding and everything else that comes with this terrible condition.

Just go on!

[ZirothTech]

Been T1 diabetic for 20 years now and it’s always fun to follow these advancements (with realistic expectations) - real time digital glucose monitoring is probably the most life changing thing I’ve experienced. Great work and super interesting history too, I’ll refer to my urine when I have high blood sugar as honey going forward 😂

[astraeanova]

All I can say is thank you for working on this and bringing it to my attention.
I've had type1 diabetes for 54 years and have been hoping for something like this every moment of those years and have been let down so many times after hearing about a great cure possibility which suddenly disappears from view so I really hope this succeeds and removes part of this burden from my life. I would even ask to be a guinea pig for when human trials start as this sounds very positive. God bless.😊

[thatretrocattt]

0:13 "Behold... BALL IN HOLE"

[linamishima]

A sentiment that I’m increasingly hearing and agreeing with is that the last century was the century of physics, but the big innovations in the next century will be in biochemistry

[theothergameygamer]

Unfortunately since there's no financial incentive for Big Pharma to cure diabetes, the best we'll ever get is the current lifetime subscription model.

[MedlifeCrisis]

This was a really lovely summary and story, especially about your involvement and hearing a bit of BTS about a science start up. I think it’s fair to say I’m a lot less optimistic about the timescales involved than you might be, and I think using words like cure or “we did it”b are premature but I hope I’m proved a big Debbie Downer. Congratulations to you and the rest of the team 👏

[MrDmadness]

Ive been hearing this for 45 years. My grandmother heard this oo for 87 years. I will believe we have a cure when there is one

[aniksamiurrahman]

Hi, Biochemist here. Theraputic peptides are very promising. The only problem is they are at least 10 times costly than the costlier 'regular' medicine. Unless we got a way to manufacture them as cheap as regular cough syrup or at least regular antibiotic, there's no medicine 4.0. And all those out there talking about trickle down from rich, just know this - brute force scaling up won't do here. Otherwise the market is already pretty massive.

[Enjoymentboy]

I have close friends who are type 1 and type 2 diabetic. Their health issues have NOTHING to do with disease but 100% to do with diet. I will NEVER understand the logic of "carbs are killing me so I'm going to keep eating them". I have a cousin who I helped go low carb and she got completely off of insulin within a few months...until her doctor told her how unhealthy that was so she started eating "healthy carbs" and started back on insulin injections. I wouldn't be the least bit shocked if someone went to their dr and said "every time I eat cyanide I almost die. What should I do?" and the dr says "Keep eating the cyanide but inject yourself with this a few times a day".