The MTHFR Gene: Why Your Vitamins Might Be Useless (And What to Do) | Ultimate Human | Ep. 96

Did you know that nearly 44-60% of the population could unknowingly carry a gene mutation that impacts their health in significant ways? The MTHFR gene mutation plays a critical role in how our bodies process folic acid, which is essential for various bodily functions, from brain health to pregnancy. If your body can’t properly convert folic acid into its active form, 5-Methyltetrahydrofolate, it can lead to a range of issues like infertility, miscarriages, ADHD, mood disorders, and digestive problems. In this episode, Gary Brecka reveals studies on how personalized supplementation can be the key to unlocking better health for you!

00:00 Intro
01:36 ​Supplementing for Deficiency
04:10 ​Methylation
06:17 ​MTHFR Gene
07:48 5-Methyltetrahydrofolate
10:36 ​S Phase Arrest
15:43 ​Factors Influencing Folate Levels
22:15 ​Genetic Polymorphism
23:28 ​Government Intervention on Folic Acid Addition to Grain Products
29:45 ​5-Methyltetrahydrofolate Bypassing Folate Insufficiency

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The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

[phyllismilligan]

have been following you for a few months now. I'm 68 years old and haven't been able to afford any testing but just an evaluation of your am seeing changes. Thank you for all you do. You are a godsend.

[DPenna]

I can attest to the gene testing. I did mine 1st of the year and started supplementing for my deficiencies. Let me tell you the honest truth. It’s changed my life for the better! Thank you Gary

[LLiving]

My son was tested by his psychiatrist when he refused to take medication for Bipolar 2 and ADHD. He tested positive for the MTHFR gene mutation and takes methyl folate and a serotonin supplement. Helps TREMENDOUSLY!

[bchbuni]

I took all the testing and confirmed several, including MTHFR and COMT. I looked into it after seeing your video and linked it back to my actions during my pregnancy when I almost ended my pregnancy. You caused a light to go on, and I wish I had known this information 26 years ago. I started Prozac the minute after I gave birth. I can now relate that problem to folic acid. I helped myself through life with the addition of Prozac and constantly felt terrible about it, and now I understand exactly what happened. Thank you!

[zolt]

Thank you Gary, I got very sick a year and a half ago from a pulled tooth. I started working with a natural path here in Canada, she sent a sample to the USA and I found out what I am deficient in. My flight or fight was high and I have ADHD. Once I watched your podcast I switched to metho vitamins and wow I feel so much better! Thank you so much!

[thonscoman]

I 2nd the comments that a video on over methylation would be so valuable, thanks for your work Gary

[Jac_wheats]

You have changed my life Gary! Thank you! I am now the CEO of my own health and I can't thank you enough! Myself and my partner have the MTHFR gene mutation. The change in supplements and diet have changed everything!!! Now looking at my partners Tyroid issues too!!

[TheAmazingDawn]

I had unexplained hypertension (diastolic over 100), systemic pain, and elevated resting heart rate (over 100), trouble sleeping. All of this for YEARS. My RHR is now around 60, BP is in the low/normal range.

My Blood Pressure SKYROCKETED when I was pregnant, I was depressed, I had issues with lactation, my son had colic, and I now KNOW it was the prenatal vitamins!!! My doctor told me to continue the vitamins while breastfeeding.

As soon as I stopped breastfeeding, my son stopped crying. I bet he’s MTHFR as well.

I am 0-10% functioning with MTHFR.

[Halfcrunchyhome]

I've shared this episode to everyone in my life ❤

[e.g.]

There is also such a thing as over-methylation!!
I started supplementing with methylated B vitamins and felt great in the beginning, but several weeks later, had incredible headaches and brain fog.
I fortunately was able to find out about niacin being able to reverse this condition.
Maybe you can post some information on this?

[firstlovemusicmn]

Thank you, Gary! After hearing about this earlier this year, I realized I was struggling with a b12 deficiency. As soon as I started supplementing for my deficiencies all of my symptoms went away. The chronic fatigue, horrible digestion, depression, brain fog, hormone imbalances, all were corrected within a few months.

[staceysmith-gsou]

Thank you so much for sharing this truth. I’m a practising dietitian for over 20 years and never knew this. I will be using this information to help many children/ adults going forward. Thank you!

[jillianbaptiste]

I get really excited about this too! I will share it with everyone and hopefully they will take it more seriously hearing it from you then me😂. Thank you for making this extremely important video and also for making it efficient and digestible for people, you rock!!

[martywarren]

Hi Gary your presentation and imparting knowledge has gotten way better and easier to understand, I am sure you have made a deliberate effort to present the information so it is easier to absorb, You were always excellent at providing info now your next level so thank you, Awsome and I always recommend your podcasts to people.

[mystrength]

Excellent Video, Tnx Dr..
soo important.. 🎉

All Gynaecologists and Maternity Health Professionals need to Know this! 🎉

[dannyeichelberger]

Gary, you pushed me down the Methylation rabbit hole after viewing the Joe Rogan podcast. I have suffered with autoimmune disease for over 15 years, seen more western medicine doctors you can count on both hands and all they did was throw me on Immunosuppresant drugs and literaly treat the symptoms. After taking the methylation test i had several SNP that impact my ability to process active folate, i was literally taking Methotrexate with a Folic Acid supplement!! this combo was killing me!! after starting a supplement regiment of Folinic Acid, B2, B12 Magnesium, Zinc and high doses of D3 40, 000IU i am feeling ten times better and now tapering off ALL medications. Your a life saver man!!!!

[cmc]

Excellent information. Thank you for presenting the research in a clear, understandable way.

[virginiaowens]

Brilliant Brilliant.
Thank you Gary Brecka

[simonw.]

Outstanding overview. Thank you so much Gary!!!

[dannyc]

Hey Gary What is the dosage for children for the 5- methyl folate?