Microhaplotypes: the next generation DNA marker

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Presented By: Daniele Podini

Speaker Biography: Prof. Podini is Associate Professor of Forensic Molecular Biology and Chair of the Department of Forensic Sciences at The George Washington University. He previously served as the Assistant Chief of the Biology Section of the Scientific Department of the Carabinieri - Italian military Armed Force. Later he created and directed the Forensic Section of Genoma, a private molecular biology laboratory in Rome. He consulted with laboratories in Italy, Turkey, Albania, Tunisia, and Algeria to aid in the establishment of Molecular Genetic Sections, and the development of specific forensic capabilities.

Webinar: Microhaplotypes: the next generation DNA marker

Webinar Abstract: Microhaplotypes (microhaps) are biomarkers less than 300 nucleotides long that display multiple allelic combinations. The main advantages of microhaps over conventional short tandem repeats (STRs) include the absence of stutter, same-size alleles within each locus, lower mutation rate, and ancestry informative alleles. These forensically relevant loci can yield a power of discrimination similar to STRs while enhancing human identification (HID), mixture deconvolution and biogeographic ancestry prediction.

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