Can PRP Injections ACTUALLY Delay Knee Replacement Surgery?

PRP injections prevent knee arthritis from getting worse. This randomized controlled trial found that a series of three platelet rich plasma injections reduced pain by up to 90% and improved function by almost 50% when used to treat symptomatic knee osteoarthritis. Furthermore they found that one series of PRP injections were able to slow down the progression of knee arthritis when compared to placebo injections.

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► ABOUT ME

Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He created a YouTube channel and blog to translate cutting edge medical knowledge and clinical research to benefit all those looking to live an active and healthy lifestyle. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.

Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.

Dr. Peng’s sports medicine clinic is located in Campbell, California.

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My content reflects my own opinion and does not represent the views or opinions of my employers or hospital systems I am affiliated with. They are meant for educational purposes only. They do not substitute for the medical advice of a physician. Always seek the advice of your physician with any questions you may have regarding your health.

[leslieadler]

This is an excellent video. I had 2 prp injections and 1 hylaronic acid. I believe prp and exercise is the best combination to make a different

[fel]

Thank you doctor for sharing this information. Very helpful and informative.

[NitroNitro]

Dr Peng, you are a tremendous communicator. Your videos are concise and very easy to understand. My wife has severe osteoarthritis on one knee. Would PRP injections be a waste of money for stage 4 bone on bone?

[hamhai]

Is PRP injection good for Medial Meniscus Radial or root tear?
Would be glad to have an answer.
Thank

[concretehoustonpro]

Dr. Ping, I've watched all your videos. Thanks for the good information.I got three PRP injections from my orthopedic surgeon for my torn meniscus about 9 months ago and it really helped.Don't know if it would of gotten better on it's own but if you have the money ( I paid $600 per injection ) I would recommend it to someone as long as they know if not a magic bullet and it will not grow back new cartilage. I think the most important information you could give to someone after PRP injections with knee issues, is to change your diet, get away from processed foods and loose weight.

[steveroberson]

The only problem is insurance doesn't cover these experimental procedures & they are really expensive !

[tedodom]

I am a male, 72 year old with advanced arthritis in my right knee as the cartilage was remove on one side, HS football (ACL broken). I am looking to use PRP to delay a knee replacement. After reviewing your and other presentations on PRP, I would like to try this. I am, however, concerned about the volume of PRP fluid proposed by a physician. The proposal was for a 15cc draw with an injection of about 5cc. My blood analysis showed a PLT count of 188 (range 130—400 K/ul). It was said that that would be all the space could take. I am not a little guy, 5'10, 250lb and active (gym 3 days/week with trainer, sauna, and outside yard work.

Should I seek a second opinion?

[albertshilton]

Dr.Peng. I have successfully used PRP 10 years ago as an alternative to rotator cuff surgery. Dr. Mark Berman in Beverly Hills was a pioneer in this treatment and passed away from COVID last year. I live on San Juan Island in Washington State now. Near Seattle. Can you suggest a physician near me? Thanks for your work on YouTube. Wish I lived in Camble CA.

[AdityaEkaputra-sx]

Dr. Peng, also could you please advise doing the PRP in Jakarta Indonesia ? Any recommended doctor ? Thank you

[scottschlemmer]

$1500 and up. Immunotherapy $10k. Stem cell $5K to $50K. Dont got the money? Suffer. If that isnt wrong I dont know what is.

[AdityaEkaputra-sx]

Hello doctor. Thank you for the information. Could you please advise is PRP can cure knee chondromalacia pattela grade 4 ?

[latifatahiri]

Is plasma injection useful when the cartilage and the cruciate ligament are injured?

[thegormlesstwit]

Thanks, Doc. Good info. Do you have vids on exercises?

[salty]

Is there any improvement in Rhematoid arthritis patient on PRP vs placebo?

[Nilani]

Hi Sir Its Used For RA Rheumatoid Arthritis Patient Its

[ericlanoue]

Hi Dr. Peng - what are your thoughts on A2M being included in PRP injections, with regards to treating osteoarthritis, in my case for the shoulders?

[lesliespagat]

Hi doctor thanks for all the info on knee prp, I’m having my injection in 2 weeks.
I haven’t received any info on the after care so your videos are a big help.
Also the doctor said only one injection is needed, so I’m going to requestion him on that.
I live in a 2 story house, at what point should can I walk the 14 stairs?
Thanks so much

[jeremypham]

hi, im 28 years old and just had knee surgery for tibial plateau fracture. do you recommend annual PRP to prevent knee arthritis? thank you very much

[larryd]

Is this going to be tried on other joints. I'm 76 and have hip and back pain?

[renuka]

Hello Dr. Peng. I am a 28 years old dancer and I have a cartilage defect in the patellofemoral compartment due to an accident. I have tried PT for over a year but I still feel a pinching pain where the damage is. I have decided to get PRP shots after watching your videos, but here you say that the symptoms return to baseline after 24 months. I don't understand, isn't the PRP supposed to regenerate the lost cartilage? If yes, then why would the symptoms return? I do not have any degenerative disorder.